Clinical Pharmacology During Pregnancy, Second Edition is written for clinicians, physicians, midwives, nurses, pharmacists and other medical professionals involved in the care of women during pregnancy. The book focuses on the impact of pregnancy on drug disposition and includes coverage of treatments for diseases of specific body systems as well as essential content on dosing and efficacy. This update includes substantially expanded sections on the ethics of pharmacological research in pregnancy and physiologic changes, along with new sections on patient reported outcomes in pregnancy, delivery and postnatal care, and the use of pharmacokinetic and pharmacodynamic approaches to estimate maternal, placental and fetal dosing.
The broad range of this book encompasses analgesics, antiasthmatics, antidepressants, heart and circulatory drugs, vitamins and herbal supplements, and more. Topics in chemotherapy and substance abuse are also covered, as are research issues, including clinical trial design and ethical considerations.
- Uses an evidence-based approach for therapeutics during pregnancy
- Presents a summary of specific medications by indication, including up-to-date information on dosing and efficacy in pregnancy for the given indication
- Includes significant new sections on physiologic changes and the ethics of pharmacological research in pregnancy
About the Editors
Dr. Mattison also serves as Associate Director of the McLaughlin Centre for Population Health Risk Assessment at the University of Ottawa. He has held academic, clinical and research appointments, including; Senior Advisor to the Director of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Medical Director of the March of Dimes; Dean of the Graduate School of Public Health at the University of Pittsburgh, Professor of Obstetrics and Gynecology and Interdisciplinary Toxicology at the University of Arkansas for Medical Sciences, and Director of Human Risk Assessment at the FDA National Center for Toxicological Research.
Dr. Lee-Ann Halbert, EdD, JD, RN, MSN, NCSN, CNM, CNE, an Associate Professor of Nursing, is a member of the faculty at the University of South Carolina Beaufort. Dr. Halbert came to the field of Nursing after finding practicing as an attorney was unfulfilling. In her time as a nurse, Dr. Halbert has focused on women’s health, in particular practicing as a Certified Nurse-Midwife, and school nursing.