Progress and Prospect of Nanocarriers

Progress and Prospect of Nanocarriers: Design, Concept, Safety and Recent Advancement examines the different nanocarriers that are currently being developed for specific applications in biomedical field for drug delivery, disease management, diagnosis and therapy. The applications of nanomedicines have been rapidly expanding in the modern medical era. Nanosized drug delivery system gained tremendous amount of clinical interest due to effective bio-distribution, enhanced pharmacokinetic and selective targeting capability which results in high therapeutic potential, low side effects, and generation of cost effective drug delivery system. Numerous effective nanocarriers have been evolving including polymeric nanoparticles, liposomes, microspheres, dendrimers, and carbon nanotubes. Despite the numerous advantageous features many elements are still to be optimized for more effective and safe drug delivery in the clinical setting. There is still the need for the development of a new generation of multifunctional nano-therapeutics with wide-ranging properties such as desired tissue penetration, remote body diagnosing as well as eradication of general and local toxicities. Along with other generalized functions, native bio functioning of nanocarriers must also be taken in accounts like hydrophilic/hydrophobic ratio, clinical target, stability, the optimal route of administration, likely dose and frequency of dosing, drug release rates, toxicity, endocytosis/exocytosis and intracellular trafficking to desired targets. Progress and Prospect of Nanocarriers: Design, Concept, Safety and Recent Advancement is a helpful reference for scientists and students in the fields of drug delivery, biomaterials and nanomedicine as well as scientists and engineers in industrial disciplines of drug delivery and drug formulation.