50 Studies Every Pediatrician Should Know

Section I: Allergy Immunology 1. Efficacy of Immunoglobulin Plus Prednisolone in Prevention of Coronary Artery Abnormalities in Kawasaki Disease

Section II: Behavioral 2. Measles, Mumps, and Rubella Vaccination and Autism 3. Treatment for adolescents with depression study (TADS) 4. The Multimodal Treatment Study of Children with Attention Deficit/Hyperactivity Disorder (MTA)

Section III: Cardiology 5. Pharmacologic Closure of a Patent Ductus Arteriosus in Premature Infants 6. The relation of overweight to cardiovascular risk factors among children and adolescents: the Bogalusa heart study

Section IV: Dermatology 7. Propranolol vs. Prednisolone for Symptomatic Proliferating Infantile Hemangiomas: A Randomized Clinical Trial Section V: Endocrinology 8. Risk Factors for Cerebral Edema in Children with Diabetic Ketoacidosis Section VI: ENT 9. A Trial of Early Ear Tube Placement in Children with Persistent Otitis Media

Section VII: General Pediatrics 10. Maintenance IV Fluid Requirements 11. Predischarge Serum Bilirubin to Predict Significant Hyperbilirubinemia in Newborns 12. Sudden Infant Death Syndrome Risk Factors: The Chicago Infant Mortality Study 13. Treatment of Acute Otitis Media in Children 14. The Human Papillomavirus Vaccine 15. Evidence of Decrease in Vaccine-Type Human Papillomavirus (HPV) and Herd Protection in Adolescents and Young Women 16. Effects of Lead Exposure in Childhood

Section VIII: Hematology 17. Iron Supplementation for Breastfed Infants 18. Transfusion Strategies for Patients in Pediatric Intensive Care Units 19. Prophylactic Penicillin in Sickle Cell Anemia

Section IX: Infectious Disease 20. Empiric Antimicrobial Therapy for Skin and Soft-Tissue Infections 21. Infants at Low Risk for Serious Bacterial Infection 22. Outpatient Treatment of Febrile Infants at Low Risk for Serious Bacterial Infection 23. Outpatient Treatment of Selected Febrile Infants Without Antibiotics 24. Neonatal Fever Without a Source 25. Serious Bacterial Infections and Viral Infections in Febrile Infants 26. Chest Radiograph and Lower Respiratory Tract Infection 27. Vidarabine Therapy of Neonatal Herpes Simplex Virus Infection 28. Early Reversal of Pediatric and Neonatal Septic Shock 29. Reduction of vertical transmission of human immunodeficiency virus (HIV) 30. Palivizumab prophylaxis against Respiratory Syncytial Virus (RSV) in high risk infants 31. The Spectrum of Bronchiolitis 32. Preventing Early-Onset Neonatal Group B Streptococcal Disease

Section X: Neonatology 33. Apgar Scoring of Infants at Delivery 34. Prophylactic Treatment with Human Surfactant in Extremely Preterm Infants

Section XI: Nephrology 35. Oral versus Initial Intravenous Antibiotics for Urinary Tract Infection in Young Febrile Children 36. Identifying children with minimal change disease (MCD) 37. Chronic renal disease following poststreptococcal glomerulonephritis

Section XII: Neurology 38. Antipyretic Agents for Preventing Febrile Seizure Recurrence 39. Febrile Seizures and Risk for Epilepsy 40. Seizure Recurrence After First Unprovoked Afebrile Seizure 41. Mortality and Childhood-Onset Epilepsy 42. Identifying Children with Low-Risk Head Injuries Who Do Not Require Computed Tomography

Section XIII: Oncology 43. Health-Related Quality of Life Among Children with Acute Lymphoblastic Leukemia

Section XIV: Ophthalmology 44. Treatment of Acute Conjunctivitis in Children 45. Screening for Amblyopia Section XV: Orthopedics 46. Differentiation Between Septic Arthritis and Transient Synovitis of the Hip in Children

Section XVI: Pulmonary 47. Steroids for the Treatment of Croup 48. Inhaled Corticosteroids for Mild Persistent Asthma 49. Inhaled Salbutamol (Albuterol) vs. Injected Epinephrine in Acute Asthma 50. Long-term Inhaled Hypertonic Saline for Cystic Fibrosis