A Guide to Hematology in Dogs and Cats

Contents 1 How to use this Guide 2 Hematology in Practice Indications for Hematology In-Clinic Versus Outside Laboratory Communicating the Need for Hematology Communicating the Results The Economics of Laboratory Testing 3 Laboratory Methods In Hematology Blood Collection Handling the Sample Blood Films Staining Common Artifacts/Issues Sample Evaluation Morphological Assessment Quantitative Methods Packed Cell Volume Total Plasma Protein Hemoglobin Concentration Manual Cell Counts Automated Cell Counters 4 Erythrocytes Overview Production Destruction Function Physiology Morphology Normal Morphology: Dog Normal Morphology: Cat Morphology in Disease Artifacts Quantity Anemia Regenerative Anemia Non-Regenerative Anemia Polycythemia 5 Neutrophils Overview Origin Function Quantity Neutropenia Neutrophilia Morphology Normal In Disease 6 Eosinophils Overview Origin Function Quantity Eosinopenia Eosinophilia Morphology 7 Basophils Overview Origin Function Quantity Basopenia Basophilia Morphology 8 Monocytes Overview Origin Function Quantity Morphology Normal In Disease 9 Lymphocytes Overview Origin Function Quantity Lymphopenia Lymphocytosis Morphology Normal Activated (Antigen-Stimulated) Lymphocytes Atypical Lymphocytes 10 Platelets Overview Laboratory Evaluation of Platelets Morphology Normal Morphology: Dog Normal Morphology: Cat Abnormal Morphology: Dog Abnormal Morphology: Cat Quantity Normal Decreased Platelet count (Thrombocytopenia) Clinical Signs of Thrombocytopenia Causes of Thrombocytopenia Increased Platelet Count (Thrombocytosis) Mechanisms of Thrombocytosis Platelet Function Disorders (Thrombocytopathia or Thrombopathia) Causes of Platelet Dysfunction Acquired Platelet Dysfunction Inherited Platelet Dysfunction 11 Interpretation of the Hemogram Introduction White Cells Red Cells Platelets 12 Case Studies 13 Self-test questions 14 Appendix - self-test answers INDEX