Advances in the Engineering of Polysaccharide Materials : by Phosphorylase-Catalyzed Enzymatic Chain-Elongation - Jun-ichi Kadokawa

Advances in the Engineering of Polysaccharide Materials

by Phosphorylase-Catalyzed Enzymatic Chain-Elongation

By: Jun-ichi Kadokawa, Yoshiro Kaneko

Hardcover | 17 April 2013 | Edition Number 1

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Polysaccharides and their related compounds are attracting much attention because of their potential for the applications as new functional materials in many research field such as medicines, pharmaceutics, foods, and cosmetics. Therefore, precision synthesis of new polysaccharides with well-defined structure is being increasingly important. For this purpose, enzymatic method is a very powerful tool because the reaction proceeds with highly stereo- and regiocontrolled manners. This book focuses on advances in the practical synthesis of polysaccharides by the phosphorylase-catalyzed chain-elongation on the basis of the viewpoint of polysaccharide engineering.

Industry Reviews

"This book covers a wide range of knowledge from the authors' vast experience in the enzymatic synthesis of polysaccharides. The authors treat with authority subjects such as vine-twining polymerization and amylose-based nanomaterials, which are certain to catch the imagination of polymer chemists of all ages. The text will serve as a useful reference for years to come."-Prof. Shin-ichiro Shoda, Tohoku University, Sendai, Japan

"Saccharide synthesis has been one of the most difficult processes in terms of the stereo- and regio-selectivity control due to the complicated structure, and actually polysaccharides were not successfully synthesized. The in vitro synthesis of saccharides in the past two decades, however, was made possible by employing enzymes as the catalyst. Hydrolases and phosphorylases are typical enzymes. This book focuses on phosphorylase-catalyzed chain elongation via glycosylation to produce poly- and oligo-saccharides having amylose chains. With these methods, it is now possible to readily prepare various new functional polysaccharide materials."-Prof. Shiro Kobayashi, Kyoto Institute of Technology, Japan


"This book covers a wide range of knowledge from the authors' vast experience in the enzymatic synthesis of polysaccharides. The authors treat with authority subjects such as vine-twining polymerization and amylose-based nanomaterials, which are certain to catch the imagination of polymer chemists of all ages. The text will serve as a useful reference for years to come."-Prof. Shin-ichiro Shoda, Tohoku University, Sendai, Japan

"Saccharide synthesis has been one of the most difficult processes in terms of the stereo- and regio-selectivity control due to the complicated structure, and actually polysaccharides were not successfully synthesized. The in vitro synthesis of saccharides in the past two decades, however, was made possible by employing enzymes as the catalyst. Hydrolases and phosphorylases are typical enzymes. This book focuses on phosphorylase-catalyzed chain elongation via glycosylation to produce poly- and oligo-saccharides having amylose chains. With these methods, it is now possible to readily prepare various new functional polysaccharide materials."-Prof. Shiro Kobayashi, Kyoto Institute of Technology, Japan

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