Bioengineering Aspects in the Design of Gas Exchangers

Comparative Evolutionary, Morphological, Functional, and Molecular Perspectives

By: John N. Maina

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Hardcover | 26 June 2011

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Hardcover
344 Pages

Dimensions(cm)
23.39 x 15.6 x 2.06

Hardcover

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This book encapsulates over three decades of the author's work on comparative functional respiratory morphology. It provides insights into the mechanism(s) by which respiratory means and processes originated and advanced to their modern states. Pertinent cross-disciplinary details and facts have been integrated and reexamined in order to arrive at more robust answers to questions regarding the basis of the functional designs of gas exchangers. The utilization of oxygen for energy production is an ancient process, the development and progression of which were underpinned by dynamic events in the biological, physical, and chemical worlds. Many books that have broached the subject of comparative functional respiratory biology have only described the form and function of the 'end-product,' the gas exchanger; they have scarcely delved into the factors and the conditions that motivated and steered the development from primeval to modern respiratory means and processes. This book addresses and answers broad questions concerning the critical synthesis of multidisciplinary data, and clarifies previously cryptic aspects of comparative respiratory biology.

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You Can Find This Book In

Non-Fiction Engineering & Technology Biochemical Engineering Biotechnology Medicine Pre-Clinical Medicine & Basic Sciences Physiology Science Biology, Life Sciences Biochemistry Life Sciences in General Evolution

Zoology & Animal Sciences Animal Physiology

Accretion and Shifts of the Levels of O₂ and CO₂ in the Biosphere	p. 1
Evolution of an Aerobic Biosphere	p. 1
Fluctuations of Oxygen Levels	p. 16
Fluctuations of Carbon Dioxide Levels	p. 19
Energy Production Versus Oxygen Toxicity: The Paradox	p. 21
Oxygen and Carbon Dioxide: Molecular Factors in Respiration	p. 26
Fundamental Principles of Gas Exchangers	p. 31
General Observations	p. 31
Mechanistic Essential: Diffusion	p. 41
Mechanistic Essential: Ventilation	p. 49
Mechanistic Essential: Perfusion	p. 55
Physicochemical Properties of Respiratory Fluid Media and Gases	p. 59
General Principles	p. 59
Water	p. 64
Air	p. 73
Oxygen	p. 74
Carbon Dioxide	p. 75
Energetic Cost of Procuring O₂ from Water and Air	p. 78
Some Molecular Aspects in the Biology of Respiration	p. 85
Development of the Mammalian Lung	p. 85
Branching Morphogenesis	p. 85
Genetic and Molecular Signaling Factors	p. 89
Development of the Avian Lung	p. 99
Development of the Insectan Tracheal System	p. 101
Development of Gas Exchangers: The Bottom Liné	p. 103
Cellular and Molecular Aspects of O2 Sensing	p. 104
Metal-Based O₂-Binding Proteins	p. 111
Gaseous Signaling Molecules	p. 120
General Considerations	p. 120
NitricOxide	p. 122
Carbon Monoxide	p. 126
Hydrogen Sulfide	p. 129
Surfactant	p. 131
Functional Designs of the Gas Exchangers	p. 141
General Considerations	p. 141
Gills	p. 151
Simple (Primitive) Gills	p. 151
Complex Gills	p. 152
Transitional (Bimodal) Breathing	p. 158
General Observations	p. 158
Air-Breathing Fish	p. 159
Lungs: General Considerations	p. 163
Amphibian Lung	p. 171
Reptilian Lung	p. 177
Mammalian (Bronchioalveolar) Lung	p. 182
Avian (Parabronchial) Lung	p. 190
Tracheal Respiration	p. 209
References	p. 223
Subject Index	p. 317
Table of Contents provided by Ingram. All Rights Reserved.

Bioengineering Aspects in the Design of Gas Exchangers

Comparative Evolutionary, Morphological, Functional, and Molecular Perspectives

At a Glance

Hardcover

Shipping

How to return your order

Defective items

You Can Find This Book In

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