Biology and Pathology of Trophoblast

By: Ashley Moffett (Editor), Charlie Loke (Editor), Anne McLaren (Editor)

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Paperback | 18 August 2011

At a Glance

Paperback
294 Pages

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24.41 x 16.99 x 1.58

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$188.77

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Originally published in 2006, this book provides an in-depth account of trophoblast: the tissue derived from the fertilised egg that nourishes and protects the developing fetus. The cells of the trophoblast have many unique qualities, and exhibit great variability across different species. It has a fascinating role in the development of the placenta and as a regulator during early growth of the embryo. These aspects are all fully covered as well as studies on why it is not rejected by the mother as 'foreign' tissue. Disorders of trophoblast during development also manifest themselves in several clinical conditions during pregnancy, including gestational trophoblastic disease and pre-eclampsia. From stem cells through to epigenetics, implantation and X-chromosome inactivation, there is a lot to be learned about trophoblast, this volume provides a detailed summary of knowledge regarding the subject.

Industry Reviews

"Readers who want a more scientific treatise on the wonders of the placenta should peruse Biology and Pathology of Trophoblast...provide succinct yet comprehensive introductions to a number of important immunologic concepts pertinent to the process of placentation and the maintenance of pregnancy. Many interesting facts about placental immunology are shared." Drucilla J. Robers, M.D., Massachusetts General Hospital, New England Journal of Medicine.

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You Can Find This Book In

Non-Fiction Science Biology, Life Sciences Family & Health Parenting: Advice & Issues Pregnancy, Birth & Baby Care Medicine Pre-Clinical Medicine & Basic Sciences Human Reproduction, Growth & Development Reproductive Medicine Clinical & Internal Medicine Gynaecology & Obstetrics

Materno-Fetal Medicine

Preface
Chair's introduction
Trophoblast cell fate specification: discussion
Stem cells: pluripotency and extraembryonic differentiation in the mouse
Epigenetic regulation of trophoblast development
Regulation of X chromosome inactivation in relation to lineage allocation in early mouse embryogenesis
Gestational Trophoblastic disease
Trophoblast and the first trimester environment
Implantation is a sticky situation
Trophoblast regulation of maternal endocrine function and behaviour
Molecular signalling in embryo-uterine interactions during implantation

Trophoblast and uterine mucosal leukocytes
Immunology of trophoblast: a reappraisal
Table of Contents provided by Publisher. All Rights Reserved.

Biology and Pathology of Trophoblast

At a Glance

Paperback

Industry Reviews

Shipping

How to return your order

Defective items

You Can Find This Book In

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