Clinical Epidemiology

Practice and Methods

By: Patrick S. Parfrey (Editor), Brendan J. Barrett (Editor)

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Paperback | 19 November 2010

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Clinical epidemiology provides the scientific basis for the practice of medicine due to its focus on the diagnosis, prognosis and management of human disease using appropriate research design, measurement and evaluation. In Clinical Epidemiology: Practice and Methods, leading experts contribute selections intended to educate researchers on how best to undertake clinical research. Divided into two categories, the volume first covers issues of design, measurement and analysis associated with various research designs, then continues with methods to better inform medical decision-making, including aggregation of multiple studies using meta-analysis, health economics, clinical practice guidelines and health technology assessment. As a part of the highly successful Methods in Molecular Biology (TM) series, this comprehensive text collects the kind of detailed, up-to-date information and implementation advice that is crucial for getting optimal results.

Essential and advantageous, Clinical Epidemiology: Practice and Methods is an ideal reference for medical practitioners, basic scientists and allied health professionals who desire to improve clinical outcomes.

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Preface	p. v
Contributors	p. ix
On Framing the Research Question and Choosing the Appropriate Research Design	p. 1
Longitudinal Studies and Determination of Risk	p. 19
Modeling Longitudinal Data, I: Principles of Multivariate Analysis	p. 39
Modeling Longitudinal Data, II: Standard Regression Models and Extensions	p. 61
The Design of Randomized Controlled Trials	p. 95
Analysis of Randomized Controlled Clinical Trials	p. 113
Evaluation of Diagnostic Tests	p. 127
Biomarkers and Surrogates in Clinical Studies	p. 137
Measurement and Analysis of Patient-Reported Outcomes	p. 155
Bias in Clinical Studies of Genetic Diseases	p. 171
Genetic Epidemiology of Complex Phenotypes	p. 187
Qualitative Research in Clinical Epidemiology	p. 203
Primer on Systematic Review and Meta-Analysis	p. 217
The Role of Health Economics within Clinical Research	p. 235
Development and Limitations of Clinical Practice Guidelines	p. 251
Basics of Health Technology Assessment	p. 263
Research Ethics for Clinical Researchers	p. 285
Budgeting, Funding and Managing Clinical Research Projects	p. 299
Index	p. 313
Table of Contents provided by Ingram. All Rights Reserved.

Clinical Epidemiology

Practice and Methods

At a Glance

Paperback

Shipping

How to return your order

Defective items

You Can Find This Book In

More in Epidemiology & Medical Statistics

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2nd Edition

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7th Edition

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Jekel's Epidemiology, Biostatistics, Preventive Medicine, and Public Health

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