CMOS Biotechnology

1. Introduction, pt. I. Microfluids for electrical engineers -- 2. Introduction to Fluid Dynamics for Microfluidic Flows -- 2.1 Introduction -- 2.2 Concepts Important to the Description of Fluid Motions -- 2.3 Electrical Networks and their Fluid Analogs -- 2.4 Basic Fluid Dynamics via the Governing Differential Equations -- 2.5 Model Flows -- 2.6 Conclusions and Outlook -- Acknowledgments -- References -- Author Biography -- 3. Micro- and Nanofluidics for Biological Separations -- 3.1 Introduction -- 3.2 Fabrication of Fluidic Structure -- 3.3 Biological Applications -- 3.4 Microfluidic Experiments -- 3.5 Microchannel Capillary Electrophoresis -- 3.6 Filled Microfluidic Channels -- 3.7 Fabricated Micro- and Nanostructures -- 3.8 Conclusions -- Acknowledgment -- References -- Author biography -- 4. CMOS/Microfluidic Hybrid Systems -- 4.1 Introduction -- 4.2 CMOS/Microfluidic Hybrid System -- Concept and Advantages -- 4.3 Fabrication of Microfluidic Networks for Hybrid Systems -- 4.4 Packaging of CMOS/Microfluidic Hybrid Systems -- 4.5 Conclusions and Outlook -- Acknowledgment -- References -- Author Biography -- pt. II. CMOS actuators -- 5. CMOS-based Magnetic Cell Manipulation System -- 5.1 Introduction -- 5.2 Principle of Magnetic Manipulation of Cells -- 5.3 Design of the CMOS IC Chip -- 5.4 Complete Cell Manipulation System -- 5.5 Experiment Setup -- 5.6 Demonstration of Magnetic Cell Manipulation System -- 5.7 Conclusions and Outlook -- Acknowledgment -- References -- Author Biography -- 6. Applications of Dielectrophoresis-based Lab-on-a-chip Devices in Pharmaceutical Sciences and Biomedicine -- 6.1 General Introduction -- 6.2 Dielectrophoresis-based Approaches -- 6.3 Dielectrophoresis based Lab-on-a-chip Platforms -- 6.4 Applications of Lab-on-a-chip to Pharmaceutical Sciences -- 6.5 Lab-on-a-chip for Biomedicine and Cellular Biotechnology -- 6.6 Future Perspectives: Integrated Sensors for Cell Biology -- 6.7 Conclusions -- Acknowledgment -- References -- Author Biography -- 7. CMOS Electronic Microarrays in Diagnostics and Nanotechnology -- 7.1 Introduction -- 7.2 Electronic Microarrays -- 7.3 Electronic Transport and Hybridization of DNA -- 7.4 Nanofabrication using CMOS Microarrays -- 7.5 Discussion and Conclusions -- References -- Author Biography -- pt. III. CMOS electrical sensors -- 8. Integrated Microelectrode Arrays -- 8.1 Introduction -- 8.2 Fundamentals of Recording of Electrical Cell Activity -- 8.3 Integrated CMOS-Based Systems -- 8.4 Measurement Results -- 8.5 Conclusions and Outlook -- Appendix -- Acknowledgment -- References -- Author Biography -- 9. CMOS ICs for Brain Implantable Neural Recording Microsystems -- 9.1 Introduction -- 9.2 Electrical Microsystem Overview -- 9.3 Preamplifier and Multiplexor Integrated Circuit -- 9.4 Digital Controller Integrated Circuit -- 9.5 Conclusions -- Acknowledgment -- References -- Author Biography -- pt. IV. CMOS optical sensors -- 10. Optofluidic Microscope -- Fitting a microscope onto a sensor chip -- 11. CMOS sensors for optical molecular imaging -- Index.