Constitutive activity in receptors and other Proteins - Part B

Volume 485

By: Melvin I. Simon (Editor)

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Hardcover | 15 November 2010 | Edition Number 1

At a Glance

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708 Pages

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22.9 x 15.2 x 3.81

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This volume of Methods in Enzymology covers the current methodology for the detection and assessment of constitutively active proteins. The chapters written by expert authors who are leaders in the field,ÿprovide hints and tricks not available in primary research publications.It is extensively referenced, with useful figures and tables throughout the volume.

A. Expert authors who are leaders in the field

B. Extensively referenced and useful figures and tables

C. Provides hints and tricks to facilitate reproduction of methods

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You Can Find This Book In

Non-Fiction Science Biology, Life Sciences Molecular Biology Biochemistry Enzymology Proteins

Identification and characterization of Steroidogenic Factor-1 inverse agonists
Assessment of inverse agonism for the angiotensin II type 1 receptor
Measurement of inverse agonism in BARs
Inverse agonism of antidepressants: in vitro and in vivo studies
Differential inverse agonism at the human muscarinic M3 receptor
Ghrelin Receptor: High Constitutive Activity and Methods for Developing Inverse Agonists
Constitutive activity and inverse agonism at the a1a and a1b adrenergic receptor subtypes
Measurement of inverse agonism of the cannabinoid receptor
Constitutively Active Thyrotropin (TSH) and Thyrotropin-Releasing Hormone (TRH) Receptors and Their Inverse Agonists
Inverse retinoid agonists and neutral antagonists
y-Aminobutyric Acid Type A (GABAA) Receptor Subtype Inverse Agonists as Therapeutic Agents in Cognition
Assays for inverse agonists in the visual system
Receptor-driven identification of novel human A3 adenosine receptor antagonists as potential therapeutic agents
Inverse agonists of steroidogenic factor SF-1
Methods to Measure G Protein Coupled Receptor Activity for the Identification of Inverse Agonists
Novel Strategies and Techniques for Constitutive Activity and Inverse Agonism
Use of Pharmacoperones to Reveal GPCR Structural Components Associated with Receptor Activation and Trafficking
Application of large-scale transiently transfected cells to functional assays of ion channels and other proteins
Quantification of RNA Editing of the Serotonin 2C Receptor (5-HT2CR) Ex Vivo
Strategies for isolating constitutively-active and dominant-negative pheromone receptor mutants in yeast
Development of a GPR23 Cell-based ß-Lactamase Reporter Assay
Computational Modeling of Constitutively Active Mutants of GPCRs: C5a Receptor
TSH receptor monoclonal antibodies with agonist, antagonist and inverse agonist activities
Current standards, variations and pitfalls for the determination of constitutive TSHR activity in vitro
Towards the Rational Design of Constitutively Active KCa3.1 Mutant Channels
Fusion proteins as model systems for the analysis of constitutive GPCR activity
Screening for Novel Constitutively Active CXCR2 Mutants and Their Cellular Effects
A method for parallel solid-phase synthesis of iodinated analogues of the cannabinoid receptor type I (CB1) inverse agonist rimonabant
Coexpression systems as models for the analysis of constitutive GPCR activity
Modelling and simulation of inverse agonism dynamics
Design and Use of Constitutively Active STAT5 Constructs
In vitro and in vivo assays of protein kinase CK2 activity
Table of Contents provided by Publisher. All Rights Reserved.

Constitutive activity in receptors and other Proteins - Part B

Volume 485

At a Glance

Hardcover

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How to return your order

Defective items

You Can Find This Book In

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