Coulometric Electrode Array Detectors for HPLC

Name: Coulometric Electrode Array Detectors for HPLC
Brand: CRC PR INC
Price: 163.5 AUD
Availability: BackOrder

By: I. H. Acworth (Editor), M. Naoi (Editor), Hasan Parvez (Editor)

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Paperback | 23 May 2001 | Edition Number 1

At a Glance

Paperback
392 Pages

Dimensions(cm)
25.15 x 17.02 x 2.06

Paperback

RRP $231.00

$163.50

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This volume examines the enhancement of high-performance liquid chromatography through the development of an advanced mode of electrochemical detection (ECD) - the coulometric electrode array - from its initial promising, yet problematic, amperometric (thin-layer) design to the highly sensitive, selective and stable coulometric (flow-through) design. Unlike amperometric electrodes, the coulometric electrode is 100 per cent efficient, and measures signals from all of the analyte passing through it, which leads to improved sensitivity as well as unique selectivity. The coulometric electrode array offers the resolution of the photodiode array with the extreme sensitivity of an electrochemical detector. The book examines the use of the coulometric electrode array, as well as its practical applications in neurosciences, food, environmental, pharmaceutical and agricultural sciences and those in the area of oxidative metabolism. This collection of papers should also provide a useful reference source to all workers in the field of HPLC and those using electrochemical detection.

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Dedication
Preface
An introduction to HPLC-based electrochemical detection: From single electrode to multi-electrode arrays
Qualitative utility of coulometric array detection: theoretical and applied aspects
HPLC with electrode array detection and its application in analytical food chemistry
The measurement of markers of oxidative damage, anti-oxidants and related compounds using HPLC and coulometric array analysis
CEAS generation of large multi-parameter metabolic databases for determining categorical process involvement of biological molecules
The application of n-EC-HPLC to the analysis of insect biogenic amines
A phylogenetic analysis of biogenic monoamines in the central nervous systems of various organisms and application to the fields of medical biochemistry
Multicomponent quantitations of monoamines and related compounds in biological fluids and CNS tissues by HPLC coupled with multi-electrode electrochemical detection
The application of the multi-electrode detection system to neurochemistry: in vivo microdialysis studies
HPLC-multi-electrochemical detection system: application to neurochemical studies in pediatrics
Neurotransmitter disturbances in Alzheimer's disease with lewy bodies
Application of the multi-electrode detection system to the monitoring of drug therapy in neurological diseases
Determination of illicit drugs and related substances by using HPLC with an electrochemical coulometric array detector
Enantioseparation of biologically active compounds by HPLC
Analysis of endogenous enantiomers of neurotoxins in clinical samples by a multi-electrode detection system with a chiral column
Electrochemical measurement of electrochemically unreactive compounds: an examination of the use of derivatives and photolysis with HPLC and coulometric detection
Subject index
Table of Contents provided by Blackwell. All Rights Reserved.

Coulometric Electrode Array Detectors for HPLC

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Paperback

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