
Critical Appraisal of Epidemiological Studies and Clinical Trials
By: Mark Elwood
Paperback | 16 March 2017 | Edition Number 4
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The book outlines the systematic review process for the establishment of causal effect within single and multiple studies. Focusing primarily on study design, it covers randomized and non-randomized trials, cohort studies, case-control studies, and surveys, showing the presentation of results including person-time and survival analysis, and issues in the selection of subjects. It then describes the process of detection and assessment of selection biases, observation bias, confounding, chance variation, and how to determine internal validity and external validity (generalizability). Statistical methods are presented in an accessible way, illustrating applications to each study design. Positive features of causation including strength, dose-response, and consistency are also discussed.
The final chapters provide six examples of critical appraisals of major studies, encompassing randomized trials, prospective and retrospective cohort studies, and case-control studies. Statistical issues are explained clearly without complex mathematics, and the most useful methods are summarized in the appendix, each with a worked example. Each main chapter includes self-test questions, with answers provided, making the book ideally suited to readers with no prior epidemiological or statistical knowledge.
Developed over four editions, Critical Appraisal of Epidemiological Studies and Clinical Trials is an invaluable aid to the effective assessment of new studies in epidemiology, public health, research methods, evidence-based methods, clinical medicine, and environmental health; making it essential reading for postgraduates, practitioners, and policymakers in these fields.
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ISBN: 9780199682898
ISBN-10: 0199682895
Published: 16th March 2017
Format: Paperback
Language: English
Number of Pages: 512
Audience: Professional and Scholarly
Publisher: Oxford University Press UK
Country of Publication: GB
Edition Number: 4
Edition Type: Revised
Dimensions (cm): 15.9 x 23.4 x 3.4
Weight (kg): 0.8
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This product is categorised by
- Non-FictionMedicineMedicine in GeneralPublic Health & Preventive MedicineEpidemiology & Medical Statistics
- Non-FictionMedicineMedicine in GeneralMedical Equipment & TechniquesMedical ResearchClinical Trials
- Non-FictionMedicineMedicine in GeneralHealth Systems & Services
- Non-FictionMedicineMedicine in GeneralPublic Health & Preventive Medicine