Preface
Chapter 1 Epidemiology and Aetiology of Head and Neck Cancers
Newell W. Johnson and Hemantha K. Amarasinghe
Chapter 2 Head and Neck Cancer Prevention
Fausto Chiesa, Angelo Ostuni, Roberto Grigolato, Luca Calabrese
Chapter 3 Cellular and Molecular Pathology of Head and Neck Tumors
Adel K. El-Naggar
Chapter 4 Oncogenomics/Proteomics of Head and Neck Cancers
Howard S. Moskowitz and Jennifer R. Grandis
Chapter 5 Genetics and Epigenetics of Head and Neck Cancer
Richard J. Shaw and Jagtar Dhanda
Chapter 6 Immunology of Head and Neck Cancer
Steve C. Lee and Robert L. Ferris
Chapter 7 HPV and EBV in Head and Neck Cancer
Jeffery Brumbaugh, Robert L. Ferris, Shen Hu
Chapter 8 Head and Neck Cancer Staging and Prognosis: Perspectives of the UICC and the AJCC
Brian O'Sullivan and Jatin P. Shah
Chapter 9 Biomarkers in Head and Neck Cancer
John Wrangle, Shanthi Marur, Arlene A. Forastiere
Chapter 10 Hypoxia in Head and Neck cancers: Clinical Relevance and Treatment
Yungan Tao and Jean Bourhis
Chapter 11 Translational Research in Head and Neck Oncology
David Sung-Hyun Yoo and David M. Brizel
Chapter 12 Preclinical Models of Head and Neck Squamous Cell Carcinoma
Michiel W.M. van den Brekel, Ms CL Zuur, Stephen P. Malkoski, and Xiao Jing Wang
Chapter 13 Morphologic Investigations in Head and Neck Cancer
Suyash Mohan and Gaurang V. Shah
Chapter 14 Ultrasound Investigations in Head and Neck Cancer Patients
Yolanda Y.P. Lee, K.T. Wong, Ann D. King, Anil T. Ahuja
Chapter 15 Functional Imaging
Ludwig G. Strauss and Antonia Dimitrakopoulou-Strauss
Chapter 16 Sentinel Node Biopsy for Head and Neck Cancer
Lee Alkureishi and Gary L. Ross
Chapter 17 Approaches to Supportive Care
Barbara A. Murphy
Chapter 18 Intensity-Modulated Radiation Therapy for Head and Neck Cancer
Nancy Lee, Daniel Gomez, Edward J. Shin, K.S. Clifford Chao
Chapter 19 Principles of Systemic Chemotherapy for Squamous Cell Head and Neck Cancer
Cristina P. Rodriguez and David J. Adelstein
Chapter 20 Molecular Targeted Therapies in Head and Neck Cancer
Vinai Gondi, Anne M. Traynor, Paul M. Harari
Chapter 21 Phase I Study Methodology in Head and Neck Oncology
Christophe Le Tourneau and Lillian L. Siu
Chapter 22 Evidence-Based Head and Neck Oncology: Principles and Pitfalls
Soren M. Bentzen
Chapter 23 Programs of Organ and Function Preservation
Jean-Louis Lefebvre
Chapter 24 Multidisciplinary Approach of Unresectable Disease
Ricardo Hitt, Blanca Homet, Robert I. Haddad
Chapter 25 Laser Endoscopic Treatment
Pierre R. Moreau and Pierre H. Demez
Chapter 26 Multidisciplinary Management of Skull Base and Superstructure Tumors
Giulio Cantu, Carlo L. Solero, Stefano Riccio, Sarah Colombo, Madia Pompilio
Chapter 27 Multidisciplinary Management of Oral Cavity and Maxillary Sinus Cancers
Alexander D. Rapidis
Chapter 28 Management of Nasopharyngeal Carcinoma
Anne W.M. Lee, Wai Tong Ng, Tsz Kok Yau, Stephen C.K. Law, William I. Wei
Chapter 29 Multidisciplinary Management of Oropharynx Carcinomas
Beth M. Beadle and David I. Rosenthal
Chapter 30 Multidisciplinary Management of Hypopharyngeal Carcinoma
Marc Hamoir, Jean-Pascal Machiels, Sandra Schmitz, Vincente Gregoire
Chapter 31 Cancers of the Larynx: Tis, T1, T2: Evaluation and Management
Carol M. Lewis, Ollivier Laccourreye, Randal S. Weber, F. Christopher Holsinger
Chapter 32 Diagnosis and Multidisciplinary Treatment of Laryngeal Cancers
Nabil F. Saba, J. Trad Wadsworth, Jonathan J. Beitler, Fadlo R. Khuri
Chapter 33 Principles and New Approaches in Surgical Reconstruction
Christina Kenney Magill and Bruce H. Haughey
Chapter 34 Multidisciplinary Treatment of the Neck
Remco de Bree, Johannes A. Langendijk, C. Rene Leemans
Chapter 35 Postoperative Management of High-Risk Resectable Head & Neck Cancer
Jay S. Cooper
Chapter 36 Management of Salivary Gland Cancer
Laura D. Locati, Marco Guzzo, Patrizia Olmi, Lisa Licitra
Chapter 37 Head and Neck Melanoma
Genevieve A. Andrews and Jeffery N. Myers
Chapter 38 Cervical Lymph Node Metastases of Squamous Cell Carcinoma from an Unknown Primary Site
Nicholas Pavlidis and George Plataniotis
Chapter 39 The Management of Thyroid and Parathyroid Cancers
Ranee Mehra, Charu Aggarwal, Roger B. Cohen
Chapter 40 Head and Neck Paragangliomas
Matthew O. Old and James L. Netterville
Chapter 41 Treatment of the Elderly Head and Neck Cancer Patient
Jean-Claude Horiot and Matti S. Aapro
Chapter 42 Interstitial Radiation Therapy in Cancer of the Oropharynx and Oral Cavity
Peter C. Levendag, David N. Teguh, Paul I.M. Schmitz
Chapter 43 Proton Beam Therapy for Head and Neck Cancer
Danielle N. Margalit, Judy A. Adams, Annie W. Chan
Chapter 44 Normal Tissue Complications and Protection in Head and Neck Cancer Patients
Andy Trotti, Nikhil Rao, Avraham Eisbruch, David I. Rosenthal
Chapter 45 Rehabilitation of Heavily Treated Head and Neck Cancer Patients
Rachael E. Kammer and JoAnne Robbins
Chapter 46 Salvage Therapy in Head and Neck Cancer Patients
Saba Aftab, Rod Rezaee, Pierre Lavertu
Chapter 47 Systemic Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck
Jan B. Vermorken
Chapter 48 Best Supportive Care for Palliative Treatment
Michaela Salzwimmer
Chapter 49 Quality of Life in Head and Neck Cancer Patients
Jolie Ringash
Chapter 50 Quality Assurance of Clinical Trials in the Management of Cancer in the Head and Neck
Thomas J. FitzGerald, Maryann Bishop-Jodoin, Marcia M. Urie, Kenneth Ulin, Geoffrey S. Ibbott, James A. Purdy, Joel H. Saltz, Lester J. Peters, M. Giulia Cicchetti, Mitchell Schnall, Joseph Deasy, Walter R. Bosch, Michael V. Knopp, Lawrence H. Schwartz, Keith S. White, Richard Hanusik, Sandra K. Kessel, Karen Morano, Fran Laurie