Heat Shock Protein-Based Therapies

Contents Contributors Preface SECTION I: HEAT SHOCK PROTEIN HSP27-BASED THERAPIES 1 HSP27 as a Therapeutic Target of Novel Inhibitors and Dietary Phytochemicals in Cancer Elena Arechaga-Ocampo and Cesar Lopez-Camarillo 2 Heat Shock Protein 27 (HSP27, HSPB1) is Up-Regulated by Targeted Agents and Confers Resistance to Both Targeted Drugs and Chemotherapeutics Daniele Musiani, John D. Konda, Simona Pavan, Erica Torchiaro, Jessica Erriquez, Martina Olivero and Maria F. Di Renzo 3 Heat Shock Proteins and Cancer: Plant Based Therapy Evren Onay-Ucar SECTION II: HEAT SHOCK PROTEIN HSP60-BASED THERAPIES 4 Chaperonotherapy for Alzheimer's Disease: Focusing on HSP60 Francesco Cappello, Antonella M. Gammazza, Silvia Vilasi, Maria G. Ortore, Pier L. San-Biagio, Claudia Campanella, Andrea Pace, Antonio P. Piccionello, Giulio Taglialatela, Everly C. De Macario and Alberto J. l. Macario 5 Secreted and Circulating Cell Stress Proteins in the Periodontal Diseases Brian Henderson, Nikos Donos, Luigi Nibali and Frank Kaiser SECTION III: HEAT SHOCK PROTEIN HSP70-BASED THERAPIES 6 The Role of Heat Shock Protein 70 in Infection and Immunity Jose Rey-Ladino, Abiola Senok, Abdullah Sarkar and Ahlam Al Shedoukhy 7 Potential Cytoprotective Effects of Heat Shock Proteins to Skeletal Muscle John P. Vardiman, Philip M. Gallagher and Jacob A. Siedlik 8 Heat Shock Proteins in Triple-Negative Breast Cancer (TNBC) TreatmentPunit Kaurunit Kaur, Tarundeep arundeepSinghingh, Moses Galukandealukande, Sunil Krishnanrishnan and Alexzander A. A. Asealexzander Asea 9 Heat Shock Proteins in Multiple Sclerosis Pathogenesis: Friend or Foe? Rosaria Tinnirello, Giuseppina Turturici, Gabriella Sconzo, Walter Spinello, Alexzander A. A. Asea and Fabiana Geraci 10 New Indications for HSP90 and HSP70 Inhibitors as Antiviral Drugs Matthew K. Howe and Timothy A. J. Haystead 11 Potential Applications of Nanoparticles for Hyperthermia Caio C. Quini and Sunil Krishnan SECTION IV: HEAT SHOCK PROTEIN HSP90-BASED THERAPIES 12 Gene Therapy Against HSP90: Glucocorticoid Receptor-Assisted Cancer Treatment Susanta S. Adhikari, Sujan K. Mondal and Rajkumar Banerjee 13 Potential of HSP90 Inhibitors to Treat Neurofibromatosis-Related Tumors Jeremie Vitte and Marco Giovannini 14 Role of Heat Shock Protein 90 in the Cause of Various Diseases: A Potential Therapeutic Target Subhankar Paul 15 HSP90 Inhibitor-Based Strategies for Cancer Therapy: Advancing Toward Clinical Impact David A. Proia and Richard C. Bates 16 Molecular Survival Strategies of Organisms: HSP and Small Molecules for Diagnostics and Drug Development Andreas Kirschning, Johanna-Gabriela Walter, Frank Stahl, Emilia Schax, Thomas Scheper, Pooyan Aliuos and Carsten Zeilinger 17 Targeting Heat Shock Proteins in Colorectal Cancer Sheah L. Lee, Nina C. Dempsey-Hibbert, Dale Vimalachandran, Terence D. Wardle, Paul Sutton and John H. H. Williams Index