Ion-Pair Chromatography and Related Techniques : Analytical Chemistry - Teresa Cecchi

Ion-Pair Chromatography and Related Techniques

By: Teresa Cecchi

Hardcover | 15 October 2009 | Edition Number 1

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Ion-Pair Chromatography (IPC) is a rapidly evolving method for difficult analyses of organic and inorganic ions and ionogenic, neutral, and zwitterionic compounds. The possibilities for this technology continue to grow as novel ion-pair reagents and strategies are introduced at an accelerated level. Compensating for a dearth in the literature, Ion-Pair Chromatography and Related Techniques details the basics and the evolution of this established and easily tunable technique and explains its influence on similar methods.

Theoretical modeling to application

Providing a thorough exploration of the multiplicity of interactions involved in an IPC system, this book emphasizes the progress from theoretical modeling to application. It explores the practical potential of IPC in the life science, medicine, pharmacology, forensic, food, and environmental sectors. It examines the upgrade of column technology and instrumentation to improve data quality and to increase sample throughput. The book also compares IPC to other instrumental methods of analysis and discusses the rising importance of the ion-pair concept in different analytical techniques.

Future endeavors

IPC has the potential to have lasting impact in the field of chromatography. Distilling the knowledge gained from preeminent research, this volume is a critical resource that is destined to stimulate future endeavors by separation scientists working in the area of high performance liquid chromatography.

Industry Reviews

"... provides a broad coverage of the subject of IPC with regard to theoretical features, the parameters influencing the results and the applications. The reader will find a discussion of all aspects of IPC, beginning with the theoretical basis of this technique and its retention mechanism. The author introduces to the reader all the issues connected with stationary phases, ionpair reagents, organic modifiers, the pH of the eluent, temperature, and various detection techniques which may be used in IPC. One can also find much practical advice on how to start with IPC and how to improve results by the use of IPC."
-Analytical and Bioanalytical Chemistry, April 2012

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