Large-Scale Optimization with Applications

Part III: Molecular Structure and Optimization

By: Lorenz T. Biegler (Editor), Thomas Coleman (Editor), Andrew r. Conn (Editor)

Write A Review

Paperback | 30 September 2012

At a Glance

Paperback
228 Pages

Dimensions(cm)
23.39 x 15.6 x 1.22

Paperback

$187.31

or 4 interest-free payments of $46.83 with

Aims to ship in 7 to 10 business days

Many important molecular conformation problems, such as protein folding, are expressed as global minimization problems. It is the fact that local minimization is insufficient, that markedly differentiates this volume from the previous two. Unfortunately, global minimization problems that result from models of molecular conformation are usually intractable. For example, simple 1-dimensional versions of distance conformation problems are NP-hard. Nevertheless, there has been significant recent progress in the design of promising heuristic strategies (often involving the use of high- performance parallel computers) for computing approximate global minimizers. The purpose of the sessions represented in this volume was to discuss the new algorithmic advances for global minimization in the context of protein folding and related molecular minimization problems. Emphasis was on practical shortcomings of current approaches, outstanding problems and questions, and the use of high-performance parallel computers.

Shipping

	Standard Shipping	Express Shipping
Metro postcodes:	$9.99	$14.95
Regional postcodes:	$9.99	$14.95
Rural postcodes:	$9.99	$14.95

How to return your order

At Booktopia, we offer hassle-free returns in accordance with our returns policy. If you wish to return an item, please get in touch with Booktopia Customer Care.

Additional postage charges may be applicable.