Mammalian Chromosome Engineering

1. Developing Extrachromosomal Gene Expression Vector Technologies: An Overview Richard Wade-Martins 2. High Capacity Extrachromosomal Gene Expression Vectors Olivia Hibbitt and Richard Wade-Martins 3. Naturally Occurring Minichromosome Platforms in Chromosome Engineering: An Overview Elena Raimondi 4. Chromosome Transfer Via Cell Fusion Marianna Paulis 5. Insertional Engineering of Chromosomes with Sleeping Beauty Transposition: An Overview Ivana Grabundzija, Zsuzsanna Izsvak, and Zoltan Ivics 6. Rodent Transgenesis Mediated by a Novel Hyperactive Sleeping Beauty Transposon System Lajos Mates 7. Construction and Use of a Bottom-Up HAC Vector for Transgene Expression Masashi Ikeno and Nobutaka Suzuki 8. De novo Generation of Satellite DNA-Based Artificial Chromosomes by Induced Large-Scale Amplification Erika Csonka 9. Downstream Bioengineering of ACE Chromosomes for Incorporation of Site-Specific Recombination Cassettes Amy L. Greene and Edward L. Perkins 10. Chromosome Engineering with Lambda-Integrase Mediated Recombination System: The ACE System Tunde Praznovszky 11. Dendrimer Mediated Transfer of Engineered Chromosomes Robert L. Katona 12. Engineered Chromosomes in Transgenics Peter Blazso, Ildiko Sinko, and Robert L. Katona 13. Transfer of Stem Cells Carrying Engineered Chromosomes with XY Clone Laser System Ildiko Sinko and Robert L. Katona 14. Mammalian Artificial Chromosomes and Clinical Applications for Genetic Modification of Stem Cells: An Overview Robert L. Katona, Sandra L. Vanderbyl, and Carl F.Perez 15. Engineered Mammalian Chromosomes in Cellular Protein Production: Future Prospects Malcolm L. Kennard