Mass Spectrometry in Chemical Biology

Evolving Applications

By: Norberto Peporine Lopes (Editor), Ricardo Roberto da Silva (Editor)

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Hardcover | 22 November 2017

At a Glance

Hardcover
312 Pages

Dimensions(cm)
16.3 x 24.0 x 2.5

Hardcover

$576.50

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Introduction; Introduction to mass spectrometry instrumentation and methods used in chemical biology; Metabolomics; Proteomics; Mass spectrometry to discover natural products; Applications of mass spectrometry in synthetic biology; Studying enzyme mechanisms using mass spectrometry: Introduction; Studying enzyme mechanisms using mass spectrometry: Applications; Databases; Future perspectives; Mass spectrometry is one of the most widespread technologies in chemistry and has been increasingly used in biology with the rise of omics sciences. This book summarizes important mass spectrometry related methodological approaches and applications in the field of chemical biology. It provides an important compendium of theoretical and experimental techniques that can be applied to study a wide range of problems in biological systems and would therefore be of great interest to students and researchers in the fields of analytical chemistry, biochemistry and chemical biology. Mass spectrometry is one of the most widespread technologies in chemistry and has been increasingly used in biology with the rise of omics sciences. This book summarizes some important methodological approaches in mass spectrometry and applications in the field of chemical biology.
The core chapters build on basic concepts introduced in the opening chapter and explore established fields such as high throughput screening, proteomics and metabolomics. Emerging applications of mass spectrometry in elucidating biosynthetic pathways, enzyme mechanisms and protein-protein interactions are then presented. Connections between these diverse research fields are highlighted throughout. The book concludes with a discussion of databases and future perspectives.
This book will be a useful tool to early chemical biology researchers wishing to incorporate mass spectrometry as a tool in their research.

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