Mathematical Models and Immune Cell Biology

By: Carmen Molina-ParÃs (Editor), Grant Lythe (Editor)

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Hardcover | 6 May 2011

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Hardcover
424 Pages

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23.39 x 15.6 x 2.39

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Whole new areas of immunological research are emerging from the analysis of experimental data, going beyond statistics and parameter estimation into what an applied mathematician would recognise as modelling of dynamical systems. Stochastic methods are increasingly important, because stochastic models are closer to the Brownian reality of the cellular and sub-cellular world.

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You Can Find This Book In

Non-Fiction Medicine Clinical & Internal Medicine Diseases & Disorders Immunology Science Biology, Life Sciences Biochemistry Proteins Life Sciences in General Computing & I.T.Computer Science

Contributors	p. xi
List of Abbreviations	p. xv
Thymocyte Development	p. 1
A Review of Mathematical Models for T Cell Receptor Triggering and Antigen Discrimination	p. 25
Dynamic Tuning of T Cell Receptor Specificity by Co-Receptors and Costimulation	p. 47
T Cell Activation and Function: Role of Signal Strength	p. 75
The Cyton Model for Lymphocyte Proliferation and Differentiation	p. 107
Modelling Intravital Two-Photon Data of Lymphocyte Migration and Interaction	p. 121
Modelling Lymphocyte Dynamics In Vivo	p. 141
Continuous-Time Birth and Death Processes: Diversity Maintenance of Naive T Cells in the Periphery	p. 171
Multivariate Competition Processes: A Model for Two Competing T Cell Clonotypes	p. 187
Stochastic Modelling of T Cell Homeostasis for Two Competing Clonotypes Via the Master Equation	p. 207
Dendritic Cell Migration in the Intestinal Tract	p. 227
Reassessing Germinal Centre Reaction Concepts	p. 241
B Cell Strategies of Ag Recognition in a Stratified Immune System	p. 259
Dynamics of Peripheral Regulatory and Effector T Cells Competing for Antigen Presenting Cells	p. 275
Mathematical Models of the Role of IL-2 in the Interactions Between Helper and Regulatory CD4+ T Cells	p. 305
A Physicist's Approach to Immunology	p. 339
Timescales of the Adaptive Immune Response	p. 351
Using Mathematical Models to Explore the Role of Cytotoxic T Lymphocytes in HIV Infection	p. 363
Viral Immunity and Persistence	p. 383
Index	p. 405
Table of Contents provided by Ingram. All Rights Reserved.

Mathematical Models and Immune Cell Biology

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Hardcover

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