Mechanochemistry and Emerging Technologies for Sustainable Chemical Manufacturing

By: Evelina Colacino (Editor), Felipe Garcia (Editor)

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Paperback | 9 October 2024

At a Glance

Paperback
346 Pages

Dimensions(cm)
25.4 x 17.78 x 1.83

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This unique volume describes advances in the field of mechanochemistry, in particular the scaling up of mechanochemical processes. Scalable techniques employed to carry out solvent-free synthesis are evaluated. Comparability to continuous flow chemistry, the current industrial benchmark for continuous efficient chemical synthesis, is presented.The book concludes that mechanochemical synthesis can be scaled up into a continuous, sustainable process. It demonstrates that large-scale mechanochemistry can meet industrial demands, especially in the pharmaceutical industry.

Features

Mechanochemistry is rapidly developing as a multidisciplinary science on the borderline between chemistry, materials science and environmental science
This unique text focuses on mechanochemistry with the ability to scale up and illustrates how mechanochemical synthesis is no longer an obstacle
This timely book highlights recent advancements describing what can be achieved in chemical synthesis
Mechanochemistry enables the synthesis of multiple polymorphic crystalline forms in the production of drugs in the form of tablets or granules in capsules

Industry Reviews

Mechanochemistry and Emerging Technologies for Sustainable Chemical Manufacturing by Colacino, Garcia and coworkers is a great read for chemists of all levels that discusses not only what technologies we should be investigating as scientists but where they can be best implemented. The text discusses a varying amount of technologies while showing great examples of complexity. The attention to detail on the different areas of scale up, large scale manufacturing, and long lasting impacts of chemical synthesis make this text great for early career researchers to be more aware of where chemistry can make changes while also showing mid/late career chemists how we can be more conscious about our efforts. This will be a great text to use for examples in upper level organic synthesis courses or green chemistry courses that seek to include new technologies.

- Isaiah R. Speight, Ph.D., Assistant Professor of Chemistry, Department of Chemistry, William & Mary, Williamsburg, VA, USA

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