Methods in Enzymology, Volume 522

GPCR Modeling * The Protein Local Optimization Program and G-Protein Coupled Receptors: Loop Restoration and Applications to Homology Modeling * Modeling Active GPCR Conformations * Molecular Modeling of Adenosine Receptors *Predicting G Protein-Coupled Receptors Families using Different Physiochemical Properties and Pseudo Amino Acid Composition Computational Design and Experimental Characterization of GPCR Segment Models GPCR Interactions with Other Molecules and Cross-Talk * G Protein-Coupled Receptor Interaction with Small GTPases * Quantification of Receptor Tyrosine Kinase Activation and Transactivation by G Protein Coupled Receptors Using Spatial Intensity Distribution Analysis (SpIDA) * NMR Methods for Detection of Small Molecule Binding to RGS4 * Group II Activators of G-protein Signaling: Monitoring the Interaction of Ga with the G-Protein Regulatory Motif in the Intact Cell * Homogeneous Time-Resolved Fluorescence Assay to Probe Folded G Protein-Coupled Receptors * cAMP Biosensors Applied in Molecular Pharmacological Studies of G Protein-Coupled Receptors * Rhodopsin-Lipid Interactions Studied by NMR GPCR Bias * Biasing the Parathyroid Hormone Receptor: Relating In Vitro Ligand Efficacy to In Vivo Biological Activity Virtual Screening * Application of Monte Carlo-based Receptor-Ensemble Docking to Virtual Screening for GPCR Ligands * From Heptahelical Bundle to Hits from the Haystack: Structure-Based Virtual Screening for GPCR Ligands GPCR Activation * Kinetics and Dynamics in the G-Protein Coupled Receptor Signaling Cascade * Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy of G Protein-Coupled Receptors * Post-Translation Modification of G Protein-Coupled Receptor in Relationship to Biased Agonism * Protein S-Nitrosylation Measurement