Overview | p. 1 |
Comparative Digestive Physiology of Dogs and Cats | p. 5 |
Introduction | p. 5 |
Digestive Compartments and Functions | p. 6 |
Mouth | p. 6 |
Esophagus | p. 7 |
Stomach | p. 7 |
Gastric Emptying | p. 8 |
Small Intestine, Pancreas, and Liver | p. 8 |
Large Intestine | p. 10 |
Hormonal Aspects of Digestion | p. 12 |
Measurement of, and Factors Affecting, Digestibility | p. 12 |
References | p. 17 |
Feeding Behavior of Dogs and Cats | p. 22 |
Food Ingestion by Feral Dogs and Cats | p. 22 |
Diurnal Rhythms, and Feeding and Drinking Patterns | p. 22 |
Role of Imprinting and Social Factors on Feeding Behavior | p. 23 |
Dietary Choice, Palatability, Learned Taste Aversions, and Preferences | p. 24 |
Control of Food Intake | p. 25 |
Feeding Recommendations | p. 25 |
References | p. 26 |
Energy | p. 28 |
Introduction | p. 28 |
Energy Evaluation and Requirements: Two Ways of Looking at the Issue | p. 28 |
Energy Evaluation | p. 28 |
Methods of Estimating Energy in Food | p. 28 |
Prediction of Energy Content | p. 29 |
Energy Requirements of Dogs | p. 33 |
Definitions | p. 33 |
Basis for Establishing Energy Requirements | p. 33 |
Basal Metabolic Rate | p. 34 |
Diet-Induced Thermogenesis and Resting Fed Metabolic Rate | p. 35 |
Adult Maintenance | p. 35 |
Gestation | p. 36 |
Lactation | p. 37 |
Growth | p. 38 |
Physical Activity | p. 39 |
Energy Requirements of Cats | p. 39 |
Basis for Establishing Energy Requirements | p. 39 |
Basal Metabolic Rate and Dietary Thermogenesis | p. 40 |
Adult Maintenance | p. 40 |
Gestation | p. 42 |
Lactation | p. 42 |
Growth | p. 45 |
Energy Deficiency and Excess in Dogs and Cats | p. 45 |
Body Condition | p. 45 |
References | p. 45 |
Carbohydrates and Fiber | p. 49 |
Definition, Classification, and Measurement | p. 49 |
Absorbable Carbohydrates | p. 49 |
Digestible Carbohydrates | p. 49 |
Fermentable Carbohydrates | p. 49 |
Nonfermentable Carbohydrates | p. 51 |
Absorbable Carbohydrates (Monosaccharides and Sugar Alcohols) | p. 51 |
Presence in Foodstuffs | p. 51 |
Digestion, Absorption, and Utilization | p. 51 |
Factors Affecting Digestibility, Absorption, and Utilization | p. 51 |
Nutritive Value | p. 52 |
Physicochemical Effects | p. 52 |
Physiological Effects | p. 52 |
Health-Related Characteristics | p. 54 |
Digestible Carbohydrates (Disaccharides, Certain Oligosaccharides, and Nonstructural Polysaccharides) | p. 54 |
Presence in Foodstuffs | p. 54 |
Digestion, Absorption, and Utilization | p. 54 |
Factors Affecting Digestibility, Absorption, and Utilization | p. 55 |
Nutritive Value | p. 57 |
Physicochemical Effects | p. 57 |
Physiological Effects | p. 58 |
Health-Related Characteristics | p. 59 |
Fermentable Carbohydrates (Lactose, Certain Oligosaccharides, Dietary Fibers, and Resistant Starch) | p. 60 |
Presence in Foodstuffs | p. 60 |
Digestion, Absorption, and Utilization | p. 60 |
Factors Affecting Digestibility, Absorption, and Utilization | p. 61 |
Nutritive Value | p. 62 |
Physicochemical Effects | p. 62 |
Physiological Effects | p. 63 |
Health-Related Characteristics | p. 67 |
Poorly Fermentable Carbohydrates (Cellulose and Wheat Bran) | p. 69 |
Presence in Foodstuffs | p. 69 |
Digestion, Absorption, and Utilization | p. 69 |
Factors Affecting Digestibility, Absorption, and Utilization | p. 70 |
Nutritive Value | p. 70 |
Physicochemical Effects | p. 70 |
Physiological Effects | p. 70 |
Health-Related Characteristics | p. 71 |
Carbohydrates in Dog and Cat Diet Formulations | p. 72 |
References | p. 74 |
Fat and Fatty Acids | p. 81 |
Importance of Dietary Fats and Fatty Acids | p. 81 |
Types and Sources of Dietary Fats and Fatty Acids | p. 81 |
Nomenclature | p. 81 |
Sources | p. 82 |
Trans Fatty Acids | p. 83 |
Medium-Chain Triacylglycerols | p. 83 |
Conjugated Linoleic Acid | p. 83 |
Other Sources | p. 84 |
Analytical Procedures | p. 84 |
Acid Hydrolysis | p. 84 |
Extraction and Saponification of Fatty Acids | p. 84 |
Extraction for Total Lipid Analysis | p. 84 |
Fat Energy and Nutrient Density | p. 85 |
Digestion and Absorption | p. 85 |
Preduodenal Lipase | p. 85 |
Pancreatic Lipase | p. 85 |
Other Lipases | p. 86 |
Summary of Triacylglycerol Hydrolysis | p. 86 |
Absorption | p. 86 |
Digestibility | p. 87 |
Biochemical Basis of Fatty Acid Essentiality | p. 88 |
Biosynthesis | p. 88 |
Desaturation and Elongation | p. 88 |
Fatty Acid Ratios | p. 88 |
Essential Fatty Acid Utilization for Structure and Function | p. 90 |
Comparative Studies | p. 90 |
Membrane Composition and Integrity | p. 90 |
Lipid-Protein Interactions | p. 90 |
Eicosanoid Production | p. 90 |
Growth and Development | p. 91 |
Canine Studies | p. 92 |
Signs of Deficiency or Excess | p. 92 |
Skin and Hair Coat | p. 93 |
Inflammatory and Immune Cell Structure and Function | p. 94 |
Feline Studies | p. 95 |
Signs of Deficiency or Excess | p. 95 |
Evidence for Limited [Delta]6 Desaturase Activities | p. 96 |
Dietary LCPUFA and Feline Life Stage | p. 96 |
Immune, Inflammatory, and Platelet Cell Functions | p. 97 |
Requirements, Recommendations, and Allowances | p. 97 |
Essential Fatty Acids for Dogs and Cats | p. 98 |
Dogs | p. 98 |
Fat Content of Diets: Preferences, Minima, and Maxima | p. 98 |
Growth | p. 99 |
Adult Maintenance | p. 100 |
Gestation and Lactation | p. 101 |
Cats | p. 102 |
Fat Content of Diets: Preferences, Minima, and Maxima | p. 102 |
Growth | p. 102 |
Adult Maintenance | p. 103 |
Gestation and Lactation | p. 104 |
References | p. 104 |
Protein and Amino Acids | p. 111 |
Basic Concepts | p. 111 |
Introduction | p. 111 |
Structure and Function | p. 111 |
Essentiality of Amino Acids | p. 112 |
Digestibility and Bioavailability of Protein and Amino Acids | p. 112 |
Assessing Protein and Amino Acid Status | p. 114 |
Requirements, Allowances, and Tolerances of Protein and Amino Acids | p. 114 |
Role of Metabolic Adaptation in Protein and Amino Acid Nutrition | p. 114 |
Nitrogen (Crude Protein) Minimum Requirements, Recommended Allowances, and Adequate Intakes | p. 116 |
Amino Acid Minimum Requirements, Recommended Allowances, Adequate Intakes, and Safe Upper Limits | p. 120 |
Dispensable Amino Acids | p. 134 |
Amino Acid Imbalances and Antagonisms | p. 137 |
References | p. 138 |
Minerals | p. 145 |
Introduction | p. 145 |
Minerals and Acid-Base Balance | p. 145 |
Macrominerals | p. 147 |
Calcium | p. 147 |
Phosphorus | p. 152 |
Magnesium | p. 156 |
Sodium | p. 159 |
Potassium | p. 162 |
Chloride | p. 166 |
Trace Minerals | p. 168 |
Iron | p. 168 |
Copper | p. 171 |
Zinc | p. 173 |
Manganese | p. 177 |
Selenium | p. 179 |
Iodine | p. 181 |
Other Minerals | p. 184 |
Arsenic | p. 184 |
Boron | p. 184 |
Chromium | p. 184 |
Molybdenum | p. 185 |
Silicon | p. 185 |
Nickel | p. 185 |
Vanadium | p. 186 |
Miscellaneous Minerals | p. 186 |
References | p. 186 |
Vitamins | p. 193 |
Introduction | p. 193 |
Vitamin A | p. 194 |
Absorption, Transport, and Storage | p. 195 |
Biological Function | p. 196 |
Dogs | p. 197 |
Cats | p. 199 |
Vitamin D | p. 200 |
Absorption, Transport, and Storage | p. 200 |
Biological Function | p. 201 |
Dogs | p. 201 |
Cats | p. 204 |
Vitamin E | p. 205 |
Absorption | p. 206 |
Biological Function | p. 206 |
Dogs | p. 208 |
Cats | p. 209 |
Vitamin K | p. 210 |
Absorption, Metabolism, and Excretion | p. 210 |
Biological Function | p. 210 |
Dogs | p. 211 |
Cats | p. 212 |
Thiamin (Vitamin B[subscript 1]) | p. 212 |
Absorption | p. 213 |
Biological Function | p. 213 |
Dogs | p. 213 |
Cats | p. 215 |
Riboflavin | p. 216 |
Absorption | p. 216 |
Biological Function | p. 216 |
Dogs | p. 216 |
Cats | p. 217 |
Vitamin B[subscript 6] | p. 218 |
Absorption, Transport, and Storage | p. 218 |
Biological Function | p. 218 |
Dogs | p. 219 |
Cats | p. 220 |
Niacin | p. 220 |
Absorption | p. 221 |
Biological Function | p. 221 |
Dogs | p. 222 |
Cats | p. 223 |
Pantothenic Acid | p. 223 |
Absorption, Transport, and Storage | p. 223 |
Biological Function | p. 224 |
Dogs | p. 224 |
Cats | p. 225 |
Cobalamin (Vitamin B[subscript 12]) | p. 225 |
Absorption | p. 225 |
Biological Function | p. 226 |
Dogs | p. 226 |
Cats | p. 227 |
Folic Acid | p. 227 |
Absorption, Transport, and Storage | p. 228 |
Biological Function | p. 228 |
Dogs | p. 228 |
Cats | p. 229 |
Biotin | p. 230 |
Absorption | p. 230 |
Biological Function | p. 230 |
Dogs | p. 231 |
Cats | p. 231 |
Choline | p. 231 |
Absorption | p. 232 |
Biological Function | p. 232 |
Dogs | p. 232 |
Cats | p. 233 |
Ascorbic Acid | p. 234 |
Biological Function | p. 234 |
Dogs | p. 235 |
Cats | p. 235 |
Vitamin-Like Substances | p. 235 |
Vitamin Losses During Processing and Storage of Dog and Cat Foods | p. 236 |
References | p. 237 |
Water | p. 246 |
General Principles | p. 246 |
Function | p. 246 |
Regulation of Intake by Dogs and Cats | p. 246 |
Deficiency in Dogs and Cats | p. 247 |
Requirements of Dogs | p. 247 |
Requirements for Maintenance | p. 247 |
Requirements for Other Life Stages | p. 248 |
Requirements for Work and Environmental Stress | p. 248 |
Requirements of Cats | p. 249 |
Requirements for Maintenance and Other Life Stages | p. 249 |
Water and Feline Lower Urinary Tract Health | p. 249 |
Recommended Allowances | p. 249 |
Toxicity in Dogs and Cats | p. 250 |
References | p. 250 |
Special Considerations for Laboratory Animals | p. 252 |
Requirements | p. 252 |
Energy | p. 252 |
Nutrients Other Than Energy | p. 252 |
Food Selection | p. 252 |
General | p. 252 |
Certified Diets | p. 254 |
Purified and Chemically Defined Diets | p. 254 |
Foods for Specific Dietary Purposes (e.g., Medical Foods) | p. 254 |
Feeding Management | p. 255 |
Life-Stage Designation of Food | p. 255 |
Form of Food | p. 255 |
Amount Fed | p. 255 |
Frequency of Feeding | p. 256 |
Storage of Food | p. 256 |
References | p. 256 |
Physical Activity and Environment | p. 258 |
Introduction | p. 258 |
Calculations and Assumptions | p. 258 |
How Much Exercise Do Dogs and Cats Undertake? | p. 259 |
Dogs | p. 259 |
Cats | p. 260 |
Types of Exercise: Sprinting Versus Endurance | p. 260 |
Sprint Exercise Over a Distance of Less Than One Kilometer | p. 260 |
Endurance Exercise Over Distances Greater Than One Kilometer | p. 260 |
Traditional Diets Fed to Racing Dogs | p. 260 |
Sled Dogs | p. 260 |
Greyhounds | p. 262 |
Diet and Health During Exercise | p. 262 |
Effect of Exercise on Intestinal Function | p. 262 |
Exercise and Digestibility | p. 263 |
When to Feed Exercising Dogs | p. 263 |
Exercise and Body Condition | p. 265 |
Effect of Confinement and Training | p. 266 |
Energy Requirements | p. 267 |
Minimal Metabolism | p. 267 |
Anxiety | p. 267 |
Circadian Rhythms | p. 268 |
Cold-Induced Thermogenesis | p. 268 |
Nutrients in a Warm Environment | p. 272 |
Effect of Reduced Oxygen at High Altitude | p. 272 |
Effect of Exercise on Energy Requirements | p. 273 |
Effect of Exercise on Energy Required in the Absence of Exercise | p. 273 |
Energy Required for Exercise: Dynamic Exercise (Short Runs) Versus Steady-State Exercise (Long Runs) | p. 273 |
Maximal Oxygen Consumption | p. 279 |
Intensity of Exercise | p. 281 |
Field Metabolic Rate | p. 281 |
Nutrient Requirements | p. 284 |
How May Nutrient Requirements Change with Exercise or in the Cold? | p. 284 |
Sources of Energy: Fat Versus Carbohydrate | p. 285 |
Protein and Exercise | p. 287 |
Studies That Have Altered Both Fat and Protein in the Diet of Exercising Dogs | p. 291 |
Dietary Carbohydrate and Exercise | p. 292 |
Importance of Water and Water Requirements at High Ambient Temperatures | p. 292 |
Exercised-Induced Hyperthermia and the Importance of Water During Exercise | p. 293 |
Water Requirements at Rest and During Exercise | p. 294 |
Sodium, Potassium, and Chloride | p. 296 |
Fluids Containing Electrolytes | p. 298 |
Calcium, Phosphorus, and Magnesium | p. 298 |
Trace Minerals | p. 299 |
Vitamins | p. 300 |
Other Nutrients | p. 303 |
References | p. 304 |
Diet Formulation and Feed Processing | p. 313 |
Petfood Processing | p. 313 |
General Considerations | p. 313 |
Dogs | p. 313 |
Cats | p. 313 |
Petfood Categories | p. 313 |
Dry Petfoods | p. 313 |
Semi-moist Petfoods | p. 314 |
Soft-Expanded (Soft Dry) Petfoods | p. 315 |
Baked Petfoods | p. 315 |
Starch-Lipid Complexes | p. 315 |
Snacks for Pets | p. 315 |
Canned (Wet) Petfoods | p. 316 |
Homemade Diets | p. 317 |
Diet Formulation | p. 317 |
Summary | p. 317 |
References | p. 318 |
Nutrient Composition of Ingredients Used in Dog and Cat Foods | p. 319 |
References | p. 343 |
Other Food Constituents | p. 344 |
Constituents Intended for Nutritive Value | p. 344 |
Introduction | p. 344 |
Chondroprotective Agents | p. 344 |
Antioxidants | p. 345 |
Probiotics (Direct-Fed Microbials) and Enzymes | p. 347 |
Herbs and Botanicals | p. 347 |
Other | p. 348 |
Constituents Intended for Technical or Nonnutritive Effects on Food | p. 348 |
Introduction | p. 348 |
Preservatives | p. 348 |
Flavors and Extracts | p. 350 |
Colors | p. 350 |
Other Additives | p. 351 |
References | p. 351 |
Nutrient Requirements and Dietary Nutrient Concentrations | p. 354 |
Use of Nutrient Requirement Tables | p. 355 |
Recommendations Relative to ME Compared with Requirements Relative to DM | p. 355 |
Requirements Relative to ME in the Food Compared with Requirements Relative to BW | p. 355 |
Note on Bioavailability | p. 356 |
References | p. 370 |
Appendixes | |
About the Authors | p. 371 |
Acronyms and Abbreviations | p. 374 |
Index | p. 377 |
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