Oxidative Stress and Redox Signalling in Parkinsonâs Disease

Research into the role of oxidative stress and redox signaling in Parkinson's disease (PD) has exploded. A PubMed search (January 8, 2018) identifies 4972 scholarly papers on this topic. Indeed, these are exciting times both for researchers, PD patients and their families. As the human genome has been sequenced and many disease mysteries are unraveled, exciting advances in research on PD have been achieved. Of particular interest in understanding the clinical picture of PD has been the relationship between oxidative stress and the pathophysiology of PD.

The Book contains 14 chapters, addressing the topic, research strategies and models aimed at delineating molecular mechanisms of the disease. The typeface is easy to read and the visuals are of great quality. While multi-authored, I generally found all chapters to be up-to-date, providing authoritative reviews of epidemiology, pathology, and neurochemistry. The writing is generally succinct, with discussions pertinent to the topic at hand.

The book should be of interest to all individuals who are interested in PD. The Editors should be commended for their efforts to produce a comprehensive, yet easy-to-follow authoritative book on current knowledge in this ever-growing field on PD. The book is successful in bridging basic research with clinical, epidemiological, regulatory and translational research, conveying both an introductory understanding and the latest development in the field. Utmost, it seems to be designed to serve both the novice student and the expert scientist and physician. With a comprehensive and integrated view on the biology of PD, the Editors and Authors the book are likely to be instrumental in stimulating a deeper understanding and promoting renewed collaborations on this multifaceted topic, leading to improved understanding of PD.

"The book should be of interest to all individuals who are interested in PD."

"With a comprehensive and integrated view on the biology of PD, the Editors and Authors of the book are likely to be instrumental in stimulating a deeper understanding and promoting renewed collaborations on this multifaceted topic, leading to improved understanding of PD."