Henry N. Wagner, Jr. Preface...!Acknowledgments!.Contributing AuthorsContents In Brief!... Part I: The Fundamentals Normal Physiology and Variants: A Primer!...!.Daniel K. Cham, Peter S. Conti01-01: Normal Physiology01-02: Non-Oncologic Pathology01-03: Post Therapeutic Changes01-04: Foreign Body Artifact01-05: Technical Artifact Part II: Clinical Cases Adrenal Cancer!..Heidi R. Wassef02-01: 72-year-old man with previous resection of right adrenal carcinoma now being evaluated for bulk recurrent disease, evident on recent CT. Germ Cell Tumors: Choricocarcinoma and Testicular Cancer..!...Anabella S. Din, Peter S. Conti03-01: 25-year-old male status post left orchiectomy with lesions involving the back, mediastinum, abdomen and the left neck, and an elevated beta-HCG and AFP level.03-02: 26-year-old male status post orchiectomy, chemotherapy and radiotherapy.03-03: 55-year-old man status post left orchiectomy, pelvic bone resection and left groin lymph node dissection.03-04: 34-year-old woman with a history of metastatic choriocarcinoma confirmed with nodulectomy during a right thoracotomy, currently presenting with rising HCG. Brain..Sherief Gamie, Peter S. Conti04-01: 75-year-old woman with suspected temporal glioblastoma for recurrence.04-02: 73-year-old male who has a history of brain mass and pulmonary carcinoid.04-03: 81-year-old male who has a history of angiosarcoma.04-04: 38-year-old female with multiple brain lesions.04-05: 46-year-old male who has a history of suprasellar mass now presenting with left eye blindness.04-06: 21-year-old male with a seizure disorder.04-07: 62-year-old female who has a history of glioma.04-08: 53-year-old female with multiple sclerosis and worsening headache for two months. Breast Cancer!Hossein Jadvar 05-01: 53-year-old female with a history of breast cancer and fibrous histiocystoma.05-02: 57-year-old female with a history of left breast cancer, with right pleural and left mid lung metastases.05-03: 48-year-old female with reported small right axillary mass on ultrasound.05-04: 56-year-old female who has a history of breast cancer status post left lumpectomy.05-05: 36-year-old female who has a history of breast cancer and positive neck biopsy. Gynecologic Malignancies: Cervical, Uterine, and Vulvar Cancer ...!.Hossein Jadvar06-01: 32-year-old female who has a history of cervical cancer and positive pelvic and abdominal lymphadenopathy.06-02: 69-year-old woman with a history of metastatic cervical cancer in the neck and abdomen.06-03: 50-year-old female who has a history of cervical cancer with metastatic disease to lung. 06-04: 32-year-old woman s/p hysterectomy and right oophorectomy for uterine cancer and a left upper lung mass.06-05: 78-year-old female s/p vulvectomy and local radiotherapy for vulvar cancer with a subcutaneous mass in the left groin. Colorectal Cancers... Robert W. Henderson07-01: 62-year-old male with a history of colon cancer s/p chemotherapy; comparison to positive basal PET study. 07-02: 56-year-old woman with a history of colon CA status post chemotherapy and radiofrequency ablation in the liver, now with rising CEA level.07-03: 59-year-old male status post left hemicolectomy with rising CEA level.07-04: 51-year-old woman with a known metastatic disease for colon carcinoma. 07-05: 42-year-old male with a recent diagnosis of low rectal tumor by biopsy being staged with PET. Cholangiocarcinoma!..Heidi R. Wassef08-01: 74-year-old male who has a history of extrahepatic cholangiocarcinoma s/p Whipple procedure and radioablation therapy now with rising CA 19-9 level.08-02: 60-year-old male with serosal implantation. Esophageal Carcinoma.! Hossein Jadvar, Shahram Bouyadlou09-01: 52-year-old man s/p esophagectomy for esophageal carcinoma currently evaluated for adrenal adenoma versus metastasis.09-02: 51-year-old man with a recent diagnosis of esophageal CA with multiple positive biopsies in the esophagus now with two left upper lobe pulmonary nodules.09-03: 65-year-old male who has a history of esophageal and liver cancer with elevated CEA level.09-04: 63-year-old female status post esophagectomy with gastric pull-up for esophageal carcinoma.09-05: 62-year-old male who has a history of esophageal cancer status post en bloc esophagectomy and gastric pull-up now presenting with dysphasia. Gastric Cancer!...!Hossein Jadvar, Shahram Bouyadlou10-01: 64-year-old man with a history of gastric cancer, status post partial gastrectomy with a suspicious lesion in the medial segment of the left hepatic lobe. 10-02: 63-year-old male who has a history of gastric cancer with a suspicious lesion in the medial aspect of the inferior portion of the liver. Gastrointestinal Tumors...Heidi R. Wassef11-01: 43-year-old male who has a history of gastrointestinal stromal tumor.11-02: 67-year-old man with an ulcerative mass in the post-bulbar duodenum. Head and Neck Cancers!...!John L. Go12-01: 35-year-old woman who is status post left modified radical neck dissection with a diagnosis of buccal cavity squamous cell carcinoma. 12-02: 62-year-old male who has a history of squamous cell carcinoma on the face with the most recent MR demonstrating suspicious lesions involving the right lateral pons, right internal auditory canal, and left infratemporal fossa. 12-03: 44-year-old woman with a history of nasopharyngeal carcinoma. 12-04: 63-year-old male presents with an enlarged left neck lymph node and a right upper jaw pain. 12-05: 50-year-old male who has a history of oral squamous cell carcinoma status post resection. 12-06: 44-year-old woman who had a diagnosis of palate carcinoma with a right infratemporal fossa tumor recurrence on MR.12-07: 73-year-old man with a history of soft palate surgery status post maxillary sinus surgery.12-08: 59-year-old male who has a history of right parotid cancer follow by resection. 12-09: 72-year-old male who has a history of squamous cell carcinoma involving the right parotid gland status post reconstructions. 12-10: 51-year-old male who has a history of tonsillar and submandibular cancer later treated with radiation therapy. Heart Viability..Lalitha Ramanna13-01: 55-year-old male with a history of coronary artery disease status post CABG evaluation for heart viability.13-02: 73-year-old female status post myocardial infarction demonstrating a transmural infarction on a thallium scan and mild to moderate ischemia in the inferoposterior wall. Inflammatory Disease and Infection!...Lalitha Ramanna14-01: 77-year-old female with a history of ulcerative colitis presents with significant dilatation in the biliary ducts and colon. Unknown Primary Tumors !Shahram Bouyadlou, Peter S. Conti15-01: 38-year-old male who has a history of low-grade fever and episodic night sweats.15-02: 44-year-old male who has a history of an inflamed left buttock. Liver Cancer..!Heidi R. Wassef16-01: 67-year-old male who has a history of hepatic ductal cancer.16-02: 68-year-old male s/p liver transplant with suspicious lesions on MR involving the right hepatic dome and right posterior lobe of the liver.16-03: 59-year-old male s/p liver transplant with rising AFP level.16-04: 58-year old male with rising AFP level.16-05: 41-year-old with cirrhosis secondary to hepatitis-B and hepatoma being evaluated for potential liver transplant. Lung Tumors...!..!Hossein Jadvar, Sherief Gamie17-01: 57-year-old man with known right-sided malignant mesothelioma. 17-02: 55-year-old male who has a history of lung cancer status post left lung biopsy with suspected metastases in the brain and kidney.17-03: 85-year-old female who has a large mass in the left mid lung and lymphadenopathy in the left hilum, subcarcina, and azygo-esophageal space on a recent chest CT.17-04: 59-year-old male who has a history of lung cancer with a large mass in the right upper lobe and supraclavicular adenopathy. 17-05: 72-year-old female who has a history of lung cancer positive on bronchoscopy.17-06: 65-year-old man with known oat cell carcinoma being evaluated for restaging. Hematologic Malignancies: Lymphoma, Leukemia, Multiple Myeloma Robert W. Henderson18-01: 67-year-old male s/p left neck biopsy proven to be lymphoma being staged with PET.18-02: 62-year-old female with several suspicious nodules in the abdominal cavity.18-03: 64-year-old female with a recent diagnosis of lymphoma being staged with PET.18-04: 47-year-old man with diagnosis of plasmocytoma with subsequent proton therapy status post decompressive laminectomy.18-05: 42-year-old man with a history of acute myelocytic leukemia with a left neck lymph node biopsy inconclusive for malignancy.18-06: 27-year-old female who has a history of Castleman's Diseases presented with retroperitoneal adenopathy.18-07: 58-year-old male presents with several suspicious lesions involving the lung, liver, and spleen. Melanoma.Heidi R. Wassef19-01: 69-year-old woman with a history of right heel melanoma and right inguinal lymph node involvement.19-02: 75-year-old male with abnormal CT in the rib, liver and lungs bilaterally.19-03: 75-year-old woman who has Stage-III melanoma s/p ipsilateral right inguinal lymph node dissection. Thyroid Carcinoma Lalitha Ramanna20-01: 74-year-old woman s/p thyroidectomy and radioablation presenting with elevating thyroglobulin level.20-02: 49-year-old female with a history of papillary thyroid cancer s/p radiotherapy and limited neck dissection.20-03: 62-year-old male with an undifferentiated thyroid carcinoma and esophageal cancer s/p radiotherapy and chemotherapy.20-04: Remote history of thyroid carcinoma is now being evaluated for soft tissue near the thyroid area suspicious for recurrence. Muscular Skeletal Tumors..!Lalitha Ramanna, Sherief Gamie21-01: 52-year-old female has a sarcoma in the right thigh. 21-02: 80-year-old with a leiomyosarcoma.21-03: 19-year-old male who has a history of a left ankle mass positive for osteosarcoma.21-04: 43-year-old female has a right thigh angiosarcoma being evaluated for recurrence.21-05: 25-year-old male who has a history of right knee mass increasing in size. Urinary Malignancies: Renal Cell Carcinoma, Bladder Cancer.!Lalitha Ramanna22-01: 55-year-old male who has a history of renal cell carcinoma s/p left nephrectomy and chemotherapy with a new left renal mass and a nodule in the right lower lung field.22-02: 76-year-old man with a remote history of laryngeal cancer and a recently diagnosed renal cell carcinoma. 22-03: 82-year-old man s/p left nephrectomy and cystectomy for bladder cancer currently being evaluated for a new chest mass. Nerve Tumor!.Lalitha Ramanna23-01: 63-year-old female who has high-grade malignant peripheral nerve sheath tumor of the right facial nerve with recent fine needle aspiration of a right middle lobe mass positive for malignant spindle cell.23-02: 48-year-old male s/p right ulnar mass resection with primitive neuroectodermal tumor (PNET). 23-03: 39-year-old male with Schwannoma and multiple left inguinal resections.23-04: 32-year-old male presents with a left calf tumor, evaluation for metabolic activity and metastatic disease is requested. Ovarian Cancer.Hossein Jadvar24-01: 73-year-old female status post right gluteal resection from sarcoma who presents with a new right iliac mass.24-02: 74-year-old female with rising CA-125 leveled s/p hysterectomy, bilateral salpingo oophorectomy, and omentectomy and positive pelvic washing. 24-03: 69-year-old female with a history of ovarian cancer currently on Cytoxan therapy. Pancreatic Cancer..!Heidi R. Wassef25-01: 47-year-old male with a history of pancreatic cancer and liver lesions on CT.25-02: 82-year-old male with fullness in the pancreatic head on CT and bilateral cavitated pulmonary nodules. 25-03: 64-year-old woman with a history of pancreatic cancer ten years ago, status-post Whipple procedure along with a history of thyroidectomy for thyroid cancer eight years ago. Prostate Cancer...!Hossein Jadvar26-01: 50-year-old man has a prevertebral soft tissue at T-9 on CT and urinary tract symptoms. 18F-Fluoride Bone Scintigraphy. !...!Peter S. Conti27-01: 37-year-old male with a history of osteosarcoma. References!... Appendix. Reimbursement. ...Jennifer S. Keppler Index!