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Plant-Derived Antimycotics
Current Trends and Future Prospects
By: Donatella Mares, M.k. Rai
Hardcover | 6 June 2003
At a Glance
612 Pages
16.9 x 23.1 x 4.2
Hardcover
RRP $399.00
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- antifungal compounds that strengthen plant-defense systems
- traditional herbs that have revealed their antifungal properties
- newer, faster methods of screening and evaluating antifungal drugs
- natural antimycotics derived from plants in Croatia, South America, South Africa, China, India, and Fiji
- the mechanism of herbal antimycotic action
- the diversity of antimycotic efficacy in Asteraceous and Meliaceous plants
- new bioactive antifungal molecules
About the Editors | p. xiii |
Contributors | p. xv |
Foreword | p. xxi |
Preface | p. xxiii |
The Need for New Antifungal Drugs: Screening for Antifungal Compounds with a Selective Mode of Action with Emphasis on the Inhibitors of the Fungal Cell Wall | p. 1 |
Introduction | p. 1 |
Drugs of Clinical Importance: Benefits and Drawbacks | p. 3 |
Trends in the Search for New Antifungal Agents | p. 8 |
Current Methods for the Detection of Fungal Cell Wall Inhibitors | p. 15 |
Detection of New Antifungal Compounds with Inhibitory Capacity of Fungal Cell Wall Synthesis | p. 20 |
Conclusions | p. 34 |
Future Directions in the Discovery of New Antifungal Agents | p. 34 |
Natural Antimycotics from Croatian Plants | p. 49 |
Introduction | p. 49 |
Biologically Active Components of Plant Species | p. 50 |
Antimicrobial Activity of Essential Oils | p. 52 |
Methods of Antimicrobial Investigation | p. 53 |
Antifungal Activity of Essential Oils and Plant Extracts | p. 60 |
Experimental Treatment of Mycosis with Natural Antimycotics | p. 70 |
Conclusions | p. 73 |
Antimycotic Activity of the Members of Meliaceae | p. 81 |
Introduction | p. 81 |
Azadirachta indica A. Juss | p. 83 |
Melia azedarach L. | p. 100 |
Other Meliaceae Members with Fungitoxic Properties | p. 109 |
Plant-Derived Extracts and Preparations As Antimycotics | p. 117 |
Introduction | p. 117 |
Materials and Methods | p. 121 |
Microbiological Examinations | p. 123 |
Clinical Studies | p. 124 |
Results | p. 125 |
Discussion | p. 135 |
Conclusions | p. 138 |
Dermatophytes As a Tool in the Discovery of New Natural Substances to Be Used As Antimycotics: Use of Microsporum cookei As a Vehicle for Reflections on the Protoanemonin Action Mechanism | p. 145 |
Introduction | p. 145 |
The Techniques | p. 148 |
Microsporum cookei (= Nannizzia cajetani) As a Primary Test Dermatophyte | p. 150 |
Mechanism of Action | p. 155 |
Conclusions | p. 161 |
Future Directions | p. 162 |
Plant-Derived Antimycotics: Potential of Asteraceous Plants | p. 165 |
Introduction | p. 165 |
Antifungal Potential of Some Important Asteraceous Plants | p. 174 |
Sesquiterpenes As Antimycotics | p. 180 |
Mechanism of Action | p. 184 |
Conclusions and Future Perspectives | p. 185 |
Recent Advances in the Search for Antimycotic Activity in South American Plants | p. 197 |
Introduction | p. 197 |
Isolation of Antifungal Compounds from Plants | p. 199 |
Searching for Antimycotic Activity in South American Plants | p. 200 |
Conclusions and Future Directions | p. 208 |
Current State and Future Directions in Plant-Derived Antimycotics | p. 213 |
Introduction | p. 213 |
Existing Assays for Detecting Antifungal Compounds | p. 214 |
The Most Important Antifungal Compounds from Plants | p. 219 |
Conclusion | p. 223 |
Plant Screening for Light-Activated Antifungal Activity | p. 229 |
Introduction | p. 229 |
Antifungal Activity in Plant Extracts | p. 230 |
Techniques | p. 235 |
Characterization of the Bioactive Compounds | p. 242 |
Conclusions and Perspectives | p. 249 |
Antifungal Saponins from White Asparagus (Asparagus officinalis L.) Bottoms and Their Physiological Role in the Plant Defense System | p. 257 |
Introduction | p. 257 |
Techniques | p. 258 |
Antifungal Activity of Saponin Fraction from White Asparagus Bottom Cut | p. 261 |
Antifungal Activities of Asparagus Saponins and Saponin Fraction Obtained from Fresh White Asparagus Plant | p. 268 |
Relationship Between Structures and Antifungal Activities of Asparagus Saponins | p. 270 |
Antifungal Activities of White Asparagus and Physiological Role of Saponin in the Plant Defense System | p. 272 |
Conclusion and Future Directions | p. 274 |
Activity of Plant Extracts, Essential Oils, and Pure Compounds Against Fungi Contaminating Foodstuffs and Causing Infections in Human Beings and Animals: A Six-Year Experience (1995-2000) | p. 279 |
Introduction | p. 279 |
Activity on Foodstuffs | p. 280 |
Activity Against Yeasts (Candida albicans and Aspergillus niger) | p. 284 |
Veterinary Parasites | p. 289 |
Conclusions and Future Directions | p. 297 |
Antimycotic Activity of Essential Oils: The Possibility of Using New Bioactive Products Derived from Plants | p. 307 |
Introduction | p. 307 |
Biological Activity of Volatile Oils | p. 310 |
Antimicrobial Activity of Volatile Oils | p. 311 |
The Brine Shrimp Bioassay--A Simple Method for Testing of Volatile Oil Toxicity | p. 316 |
Case Studies | p. 320 |
Conclusions on Fungicidal Bioactivity of Essential Oils | p. 332 |
The Future of Molecular Plant Pathology--Gene Expression | p. 336 |
Antimycotic Potential in Some Naturally Occurring Essential Oils | p. 343 |
Introduction | p. 343 |
Cymbopogon winterianus (Citronella) | p. 344 |
Turmeric Oil | p. 346 |
Eucalyptus Oil | p. 346 |
Screening for Antifungal Activity | p. 348 |
Conclusion and Future Prospects | p. 351 |
Antimycotic Essential Oils: Impact on Skin Microflora | p. 357 |
Introduction | p. 357 |
The Techniques | p. 358 |
Impact of Essential Oils on Skin Microflora | p. 359 |
Conclusions | p. 364 |
Antimycotic Potential in Plants of Central and West Africa | p. 367 |
Introduction | p. 367 |
Central Africa: Cameroon, Republic of Congo, and Zaire | p. 368 |
Western Africa: Togo and Benin | p. 370 |
Conclusion | p. 373 |
Antimycotic Principles of Pentanema indicum (L.) Ling | p. 377 |
Introduction | p. 377 |
Morphology | p. 378 |
Chemistry | p. 378 |
The Test Organisms | p. 380 |
Vicolides As Potent Antimycotics | p. 380 |
Rapid Test Methods for Evaluation of Antifungal Activity | p. 383 |
Introduction | p. 383 |
The Techniques | p. 384 |
Benefits | p. 390 |
A New Technique for the Evaluation of Antifungal Activity of an Alcohol Extract of Eugenia caryophyllata Thunberg on Penicillium digitatum | p. 393 |
Introduction | p. 393 |
The Technique | p. 394 |
Discussion and Conclusion | p. 397 |
Palestinian Plants As a Source of Antimycotics | p. 399 |
Introduction | p. 399 |
Major Groups of Antimycotic Compounds from Plants | p. 400 |
Plants Used in Folk Medicine in Palestine for the Treatment of Skin Diseases and Ailments: An Ethnobotanical Study | p. 401 |
Review of Recent Experimental Studies on Antimycotic Activity of Some Plants Used for the Treatment of Skin Diseases in Palestinian Folkloric Medicine | p. 408 |
Experimental Work on Antimycotic Activity of Some Plants from Palestine | p. 412 |
Traditional Medicine As a Source of Antifungals | p. 421 |
Conclusions | p. 423 |
Native Use of Herbal Drugs for Treatment of Skin Diseases in Nepal | p. 429 |
Introduction | p. 429 |
Collection of Ethnobotanical Information | p. 430 |
Enumeration of Plants | p. 430 |
Diversity of Plants Used in the Treatment of Skin Infections | p. 436 |
Conclusions | p. 437 |
Future Prospects | p. 438 |
The Antimycotic Potential of Fijian Plants | p. 441 |
Introduction | p. 441 |
List of Plants Showing Antimycotic Activity | p. 442 |
Antimycotic Activity of Plants | p. 443 |
Conclusions | p. 457 |
Triterpenic Glycosides--Their Isolation Methods and Antifungal Activities | p. 459 |
Introduction | p. 459 |
Techniques | p. 460 |
Glycosides As a Pharmacodynamic Group | p. 461 |
Antifungal Activity | p. 468 |
Conclusion | p. 469 |
Future Directions | p. 470 |
Structure, Function, and Biological Activity of Rice Phytoalexins and Elicitors | p. 497 |
Introduction | p. 497 |
Phytoalexins | p. 499 |
Elicitors | p. 505 |
Conclusions | p. 513 |
Future Perspectives | p. 513 |
Antifungal Agents from Traditional Chinese Medicines Against Rice Blast Fungus Pyricularia oryzae Cavara | p. 525 |
Introduction | p. 525 |
Active TCM Extracts Against P. oryzae | p. 528 |
Antifungal Compounds 1-14 from D. collettii var. hypoglauca Against P. oryzae | p. 537 |
Antifungal Compounds 15-17 from S. nigrum Against P. oryzae | p. 541 |
Antifungal Compounds 18-23 from W. indica Against P. oryzae | p. 542 |
Conclusion | p. 544 |
Index | p. 551 |
Table of Contents provided by Rittenhouse. All Rights Reserved. |
ISBN: 9781560229261
ISBN-10: 1560229268
Published: 6th June 2003
Format: Hardcover
Language: English
Number of Pages: 612
Audience: Professional and Scholarly
Publisher: Taylor & Francis Inc
Country of Publication: GB
Dimensions (cm): 16.9 x 23.1 x 4.2
Weight (kg): 1.08
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