Protein Targeting with Small Molecules : Chemical Biology Techniques and Applications - Hiroyuki Osada

Protein Targeting with Small Molecules

Chemical Biology Techniques and Applications

By: Hiroyuki Osada

Hardcover | 23 October 2009 | Edition Number 1

At a Glance

Hardcover


$283.40

or 4 interest-free payments of $70.85 with

 or 

Aims to ship in 15 to 25 business days

<b>Discover the link between the latest chemical biology approaches and novel drug therapies!</b> <p> <i>Protein Targeting with Small Molecules: Chemical Biology Techniques and Applications</i> takes readers beyond the use of chemical biology in basic research, providing a highly relevant look at techniques that can address the challenges of biology and drug design and development. <p> This indispensable bench companion features up-to-date coverage of advances in chemistry and assesses their impact on developing new therapeutics, making it ideal for chemical biologists and medicinal chemists who are developing small molecule drugs to target proteins and treat diseases. In addition, the book examines the full range of complex biological systems and their interrelationship with chemistry, from the interaction of biological response modifiers with proteins to the chemical biology of cell surface oligosaccharides. <p> Distinguished by an overview of chemical biology that is reinforced and clarified by detailed examples and descriptions of techniques, <i>Protein Targeting with Small Molecules: Chemical Biology Techniques and Applications</i>: <ul> <li>Introduces key technologies and methods of chemical biology designed to detect the interactions of small molecules and proteins <li>Facilitates the discovery of small molecules that bind to proteins and describes the molecules' application in the investigation of biological processes <li>Presents timely coverage of the development of fluorescent probes for small molecules, as well as the generation of small molecule ligands and inhibitors <li>Reviews important techniques such as chemical genomics, target profiling, immobilization technology, detection methods, chemical inhibition, and structure-based targeting <li>Offers a compelling synopsis of data that underscores the recent progress made in the area of targeting proteins by small molecules </ul> <p> <p>
Industry Reviews
"The burgeoning are of chemical biology encompasses many subfields. While it undergoes constant changes in what it covers necessitated by the rapid changes in both chemistry and biology, one central theme has remained constant--the use of small molecules as probes of myriad biological processes. The majority of bioactive small molecules of interest to chemical biologists manifest their unique and selective biological effects through binding to and interfering with the function of proteins. As such, experimental tools and techniques for detecting and deconvoluting the interactions between small molecules and proteins are of great interest to contemporary chemical biologists. The book entitled "Protein Targetting with Small Molecules" edited by Dr. Hiroyuki Osada thus fulfills an important void in the field. In this book, different experimental approaches and techniques were reviewed by the frontline practitioners in the field. Both theoretical and practical aspects of each general technique are thoughtfully covered, which were further illustrated by specific examples. It can serve multiple purposes, as a text book for graduate level chemical biology education and a reference book for those looking for new tools to study small-molecule protein and even small molecule-pathway interactions."
?Dr. Jun Liu, Johns Hopkins University School of Medicine

"The book edited by Hiroyuki Osada, one of the foremost chemical biologists of the time, aims at covering this enormously wide field by twelve complementary reviews written by experts in their individual areas of research.... Taken together the book provides a widespread overview of numerous techniques, approaches and methods typically applied in small molecule ligand design, synthesis, screening, target identification and validation as well as applications in selected fields.... Thus, while reading the chapters, the reader is exposed to the variety of chemical, biophysical, biochemical and biological techniques typically applied in small molecule based chemical biology research.... As such, I strongly recommend the book to researchers with advanced training in chemistry, biophysics, biochemistry and biology with a desire to branch out their research into neighboring disciplines and ready to become chemical biologists."
?Prof. Dr. Herbert Waldmann, Max Planck Institute of Molecular Physiology

More in Chemistry

Rocks & Minerals : The Definitive Visual Guide - Chris Pellant
Deep Eutectic Solvents - Mohammad Jawaid

RRP $352.95

$266.50

24%
OFF
The Chemistry Book : Big Ideas Simply Explained - DK

RRP $39.99

$27.35

32%
OFF
Tihkal : The Continuation - Alexander Shulgin

RRP $54.99

$52.75

Pihkal : A Chemical Love Story : A Chemical Love Story - Alexander Shulgin
Chemistry : 5th Edition - Allan Blackman

RRP $180.95

$153.25

15%
OFF
Chemistry Essentials For Dummies : For Dummies - John T. Moore

RRP $21.95

$17.25

21%
OFF
Introductory Chemistry : 7th edition - An Active Learning Approach - Mark Cracolice
Gemstones and Minerals of Australia : Updated Edition - Lin Sutherland
Organic Chemistry : 2nd edition - Jonathan Clayden

RRP $132.95

$104.90

21%
OFF
Chemistry For Dummies : For Dummies - John T. Moore

RRP $37.95

$33.90

11%
OFF
Rocks and Minerals : An Illustrated Field Guide - Mill press Cider
Organic Chemistry I Workbook For Dummies : 2nd edition - Arthur Winter
Principles of Instrumental Analysis : 7th edition - Stanley Crouch

RRP $227.95

$179.25

21%
OFF
Chemical Principles : 8th edition - Steven S. Zumdahl

RRP $217.95

$172.35

21%
OFF