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Sex-Steroid Interactions with Growth Hormone : Serono Symposia USA - Johannes D. Veldhuis

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Sex-Steroid Interactions with Growth Hormone

By: Johannes D. Veldhuis (Editor), Andrea Giustina (Editor)

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Hardcover

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Hardcover
384 Pages

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23.39 x 15.6 x 2.24

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Sex-Steroid Interactions with Growth Hormone presents the proceedings of an international symposium held from October 22-25 in Naples, Florida. The proceedings provide new insights and concepts gained by molecular, cellular and neuroendocrine research into mechanistic interactions of the reproductive and somatotrophic axes. Chapters include discussions of the impact of sex steroids on growth hormone secretion in both children and adults; sex steroids, growth hormone releasing factor, and somatostatin; how sex steroids modulate growth hormone action on target issues; and differential effects of growth hormone secretagogues in men and women. This volume is designed for physicians, scientists and other health professionals interested or trained in clinical and basic endocrinology, growth or reproduction.

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Non-Fiction Medicine Pre-Clinical Medicine & Basic Sciences Physiology Metabolism Clinical & Internal Medicine Endocrinology Science Biology, Life Sciences Biochemistry

Preface
Contributors
Sex-Steroid - Growth Hormone Axis Interactions in Normal Female Puberty	p. 3
Sex-Steroid - Growth Hormone Interactions During Normal Male Puberty	p. 11
Impact of Testosterone Replacement on the Maturation of the Growth Hormone - IGF-I Axis	p. 20
Sex-Steroid-Hormone Modulation of the Somatotropic Axis During Normal Male Puberty	p. 32
Influence of Testosterone on the GH - IGF-I Axis in Healthy Elderly Men	p. 44
Effect of Estrogen on GH Secretion and Action in Postmenopausal Women	p. 54
Menstrual Cycle Interaction with the Growth Hormone Axis	p. 67
Growth Hormone Axis Response to Superovulation	p. 74
Androgenic Modulation of the Growth Hormone - IGF Axis and Its Impact on Metabolic Outcomes	p. 82
Proposed Mechanisms of Sex-Steroid - Hormone Neuro-modulation of the Human GH - IGF-I Axis	p. 93
The Growth Hormone Axis in Precocious Puberty	p. 122
Hypothalamic Control Mechanisms of Sexually Dimorphic Growth Hormone Secretory Patterns in the Rat	p. 133
Sex Differences in Growth Hormone-Releasing Hormone (GHRH) and Somatostatin Neurons	p. 144
Sex-Steroid Interaction with Somatostatin and GHRH in the Rat	p. 153
Sex-Steroid Effects on Primate Somatotrophs	p. 160
Sex-Steroid Effects on Perifused Pituitary	p. 172
Somatotrope Heterogeneity and Its Involvement in Growth Hormone (GH) Regulation	p. 183
Sex-Steroid and GH Interactions in the Regulation of Lipid Metabolism	p. 195
Estrogen Replacement Therapy and the Response to Human Growth Hormone	p. 202
Influence of Gender on Response to Growth Hormone Substitution Therapy in Adults with Growth Hormone Deficiency	p. 209
How Sex Steroids Modulate GH Action on Target Tissues: Long-Term Follow-up in GH-Deficient Adults	p. 219
Growth Hormone Treatment in Turner Syndrome: Rationale for Therapy	p. 227
Practical Issues of Clinical Growth Hormone Therapy in Turner Syndrome	p. 235
Influence of Gonadal Function on GH Secretion	p. 243
Endocrine Responses to GH Secretagogues in Relation to Sex and Age in Humans	p. 249
Gender Impact on the GH Response to Exercise	p. 261
Stimulated Release of GH in Normal Younger and Older Men and Women	p. 277
Genetic and Transgenic Models to Investigate the Growth Hormone Axis and Sexual Dimorphism	p. 293
Estrogen Receptor Expression in the Pituitary Gland	p. 301
Metabolic Effects of GH/IGF-I, Testosterone, and Estrogen: Studies in Children and Adults	p. 308
Innovative Quantitative Neuroendocrine Techniques	p. 318
Sexual Dimorphism of Liver Cytochrome P-450 Gene Expression: GH Pulse-Activated STAT Signaling Mechanisms	p. 327
Intracellular Signaling Networks	p. 337
Author Index	p. 343
Subject Index	p. 347
Table of Contents provided by Blackwell. All Rights Reserved.

Sex-Steroid Interactions with Growth Hormone

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Hardcover

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