Solid-Phase Synthesis

Name: Solid-Phase Synthesis
Brand: Taylor & Francis Inc
Price: 594.4 AUD
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A Practical Guide

By: Fernando Albericio (Editor)

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Hardcover | 28 April 2000 | Edition Number 1

At a Glance

Hardcover
848 Pages

Dimensions(cm)
22.86 x 15.88 x 4.45

Hardcover

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This volume provides the information needed to synthesize peptides by solid-phase synthesis (SPS) - employing polymeric support (resins), anchoring linkages (handles), coupling reagents (activators), and protection schemes. It presents strategies for creating a wide variety of compounds for drug discovery and analyzes peptides, DNA, carbohydrates, conjugates of biomolecules, and small molecules.

Industry Reviews

"Prepublication praise for Solid-Phase Synthesis. . . Both Fernando Albericio and Steven Kates, as well as most of the authors of individual chapters, are well known to members of the synthetic peptide community and the information they provide can be considered authoritative and reliable. . .. While writing this piece I had occasion to look in the manuscript for answers to two specific questions and readily found both. I intend to keep a copy of this book on my desk for ready reference and I can recommend that every peptide chemist and many classical organic chemists do the same." ---from the Foreword by R. B. Merrifield, The Rockefeller University, New York, N.Y.

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You Can Find This Book In

Non-Fiction Science Biology, Life Sciences Biochemistry Chemistry Organic Chemistry Polymer Chemistry Physical Chemistry Solid State Chemistry Engineering & Technology Biochemical Engineering

Foreword	p. iii
Preface	p. v
Contributors	p. xi
Introduction: The Impact of Genome Sequencing on Drug Discovery	p. xv
The Solid Support	p. 1
Strategy in Solid-Phase Peptide Synthesis	p. 79
Amino Acids: Alpha-Amino Protecting Groups	p. 103
Side-Chain Protecting Groups	p. 129
Solid Supports for the Synthesis of Peptides and Small Molecules	p. 197
Coupling Methods: Solid-Phase Formation of Amide and Ester Bonds	p. 275
Homodetic Cyclic Peptides	p. 331
Disulfide Formation in Synthetic Peptides and Proteins: The State of the Art	p. 365
Solid-Phase Convergent Approaches to the Synthesis of Native Peptides and Proteins	p. 377
Preparation of Glyco-, Phospho-, and Sulfopeptides	p. 419
Oligonucleotide Synthesis	p. 475
Synthesis of Oligonucleotide-Peptide Conjugates and Nucleopeptides	p. 529
The Chemistry of Peptide Nucleic Acids	p. 549
Solid-Phase Synthesis of Oligosaccharides	p. 579
Solid-Phase Synthesis of Heterocyclic Compounds from Amino Acids and Linear Peptides	p. 617
Solid-Phase Synthesis of Pseudopeptides and Oligomeric Peptide Backbone Mimetics	p. 649
Instrumentation	p. 705
The Purification of Synthetic Peptides	p. 735
Analysis of Synthetic Peptides	p. 751
The Chromatographic Analysis of Combinatorial Arrays: Parallel HPLC and HPLC-MS	p. 791
Index	p. 819
Table of Contents provided by Syndetics. All Rights Reserved.

Solid-Phase Synthesis

A Practical Guide

At a Glance

Hardcover

Industry Reviews

Shipping

How to return your order

Defective items

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