List of Contributors viii
Preface xiii
1 From Early Pioneers to the PelvEx Collaborative 1
Eanna J. Ryan and P. Ronan O’Connell
2 The Role of the Multidisciplinary Team in the Management of Locally Advanced and Recurrent Rectal Cancer 12
Dennis P. Schaap, Joost Nederend, Harm J.T. Rutten, and Jacobus W.A. Burger
3 Preoperative Assessment of Tumor Anatomy and Surgical Resectability 17
Akash M. Mehta, David Burling, and John T. Jenkins
4 Neoadjuvant Therapy Options for Advanced Rectal Cancer 32
Alexandra Zaborowski, Paul Kelly, and Brian Bird
5 Preoperative Optimization Prior to Exenteration 45
Marta Climent and Miguel Pera
6 Patient Positioning and Surgical Technology 52
Ben Creavin, Michael E. Kelly, and Desmond C. Winter
7 Intraoperative Assessment of Resectability and Operative Strategy 62
Rory Kokelaar, Dean Harris, and Martyn Evans
8 Anterior Pelvic Exenteration 73
Jan W.A. Hagemans, Jan M. van Rees, Joost Rothbarth, Cornelis Verhoef , and Jacobus W.A. Burger
9 Posterior Pelvic Exenteration 85
Werner Hohenberger, Maximilian Brunner, and Susanne Merkel
10 Total Pelvic Exenteration 90
Satish K. Warrier, Andrew C. Lynch, and Alexander G. Heriot
11 Extended Exenterative Resections Involving Bone 97
Timothy Chittleborough, Gordon Beadel, and Frank Frizelle
12 Exenterative Resections Involving Vascular and Pelvic Sidewall Structures 110
Brian K. Bednarski and George J. Chang
13 Extended Exenterative Resections for Recurrent Neoplasm 120
Peter Sagar
14 Pelvic Exenteration in the Setting of Peritoneal Disease 127
Niels Kok, Arend Aalbers, and Geerard Beets
15 Minimally Invasive Pelvic Exenteration 132
Danielle Collins, Christos Kontovounisios, Shahnawaz Rasheed, and Paris Tekkis
16 Stoma Considerations Following Exenteration 138
Gabrielle H. van Ramshorst and Jurriaan B. Tuynman
17 Reconstructive Techniques Following Pelvic Exenteration 149
Dimitrios Patsouras, Alexis Schizas, and Mark George
18 Minimizing Morbidity from Pelvic Exenteration 158
Meara Dean, Alex Colquhoun, Peter Featherstone, Nicola S. Fearnhead, and R. Justin Davies
19 Crisis Management 170
Henrik Kidmose Christensen, Mette Moller Sorensen, and Victor Jilbert Verwaal
20 Quality of Life and Patient-Reported Outcome Measures Following Pelvic Exenteration 177
Daniel Steffens, Cherry Koh, and Michael Solomon
21 Adjuvant Therapy Options after Pelvic Exenteration for Advanced Rectal Cancer 194
Ka On Lam, Jeremy Yip, and Wai Lun Law
22 Adjuvant Therapy Options after Pelvic Exenteration for Gynecological Malignancy 205
Nisha Jagasia
23 Adjuvant Therapy Options for Urological Neoplasms 214
Gregory J. Nason, Clare O’Connell, and Paul K. Hegarty
24 The Role of Re-irradiation for Locally Recurrent Rectal Cancer 223
Johannes H.W. de Wilt and Jacobus W.A. Burger
25 Palliative Pelvic Exenteration 230
Hidde M. Kroon and Tarik Sammour
26 Outcomes of Pelvic Exenteration for Locally Advanced and Recurrent Rectal Cancer 243
Awad M. Jarrar and Scott R. Steele
27 Outcomes Following Exenteration for Urological Neoplasms 255
Frank McDermott, Ian Daniels, Neil Smart, and John McGrath
28 Outcomes Following Exenteration for Gynecological Neoplasms 265
Paivi Kannisto, Fredrik Liedberg, and Marie-Louise Lydrup
29 Mesenchymal and Non-Epithelial Tumors of the Pelvis 283
Eugenia Schwarzkopf and Patrick Boland
Index 298
