Technical Proceedings of the 2004 NSTI Nanotechnology Conference and Trade Show, Volume 1

Technical Proceedings of the 2004 NSTI Nanotechnology Conference and Trade Show, Volume 1 Chapter 1: Bio Nano Systems and Chemistry Forisomes: MechanoProteins that Exert Force in Contraction and Expansion M. Knoblauch, G.A. Noll, D. Prufer, H. Jaag, M.E. Fontanellaz, I. SchneiderHuther, A.J.E. van Bel and W.S. Peters Fraunhofer Institute IME, DE Development of a SelfAssembled MusclePowered Piezoelectric Microgenerator J. Xi, E. Dy, MT Hung and C. Montemagno UCLA, US Nanosecond Pulsed Electric Fields Trigger Intracellular Signals in Human Lymphocytes P.T. Vernier, Y. Sun, L. Marcu, C.M. Craft and M.A. Gundersen University of Southern California, US Viruses as Optical Probes ES Kwak, C. Chen, C. Cheng Kao, W.L. Schaich and B. Dragnea University of Indiana, US pH Dependent Optical Properties of Surface Modified Gold Nanoparticles Using a Bovine Serum Albumin Coating Y. Xu, K.A. Linares, K. Meehan, B.J. Love and N.G. Love Virginia Polytechnic Institute and State University, US Internalization of Nanoparticles in the Middle Ear Epithelium in Response to an External Magnetic Field: Generating a Force K. Dormer, C. Seeney, A. Mamedov and F. Mondalek University of Oklahoma, Coll. of Med., US High Throughput insilico Screening against Flexible Protein Receptors H. Merlitz and W. Wenzel Forschungszentrum Karlsruhe, DE Chapter 2: Bio Nano Analysis and Characterization Overview of Overlapping Bio and Nano Technologies S. Iyer LANL, US Detection of DNA Hybridyzation with Impedance Amplifying Labels KS Ma, H. Zhou, A. Fischetti, J. Zoval and M. Madou University of California, Irvine, US Functional Nanoarrays for Protein Biomarker Profiling M. Lynch, C. Mosher, J. Huff, S. Nettikadan, J. Xu and E. Henderson BioForce Nanosciences, Inc., US An ChipbasedInstant Protein Micro Array Formation and Detection System FG Tseng, C.E. Ho, M.H. Chen, K.Y. Hung, C.J. Su, Y.F. Chen, H.M. Huang and CC Chieng National Tsing Hua University, TW HighResolution Electrochemical In Situ Printing R.D. Egeland and E.M. Southern Oxamer & Oxford Gene Technology, UK Microfabricated FluorescenceActivated Cell Sorter with Hydrodynamic Flow Manipulation H. Bang, C. Chung, J.K. Kim, S. Kim, S. Chung, DC Han and J.K. Chang School of Mechanical & Aerospace Eng., Seoul National University, KR Development of a SlugFlow PCR Chip with Minimum Heating Cycle Times S. Hardt, D. Dadic, F. Doffing, K.S. Drese, G. Munchow and O. Sorensen Institute of Microtechnology Mainz, DE Composable System Simulation of Dispersion in Complex Electrophoretic Separation Microchips Y. Wang, Q. Lin and T. Mukherjee Carnegie Mellon University, US Visualizing Individual Rhodopsin (a G ProteinCoupled Receptor) Molecules in Native Disk and Reconstituted Membranes via Atomic Force Microscopy E.J. Choi, A.J. Jin, SL Niu, P.D. Smith and B.J. Litman National Institutes of Health, US SampleShunting Based PCR Microfluidic Device PA Auroux, P.J.R. Day and A. Manz Imperial College, UK Highly Efficient Electropermeabilization of Mammalian Cells Using Microelectroporation Chip Y.S. Shin, J.K. Kim, S.H. Lim, Y.K. Lee, K. Cho, Y. Lee, S. Chung, C. Chung, DC Han and J.K. Chang Seoul National University, KR Effect of Substratum Morphology on Cell Behavior WT Su, IM Chu, JY Yang and CD Lin National Nano Device Laboratories, TW An Injector Component Model for Complete Microfluidic Electrokinetic Separation Systems R. Magargle, J.F. Hoburg and T. Mukherjee Carnegie Mellon University, US Dielectrophoresis (DEP) of Cells and Microparticle in PDMS Microfluidic Channels T.T. Kanagasabapathi, C.J. Backhouse and K.V.I.S. Kaler University of Calgary, CA Dry Microarrays: A Generalized Data Source for Genome and Proteome Analysis G. Sampath The College of New Jersey, US Molecular Simulation of DNA Microarrays an Application of 2D particle mesh Ewald algorithm T. Watanabe, M. Kawata and U. Nagashima National Institute of Advanced Industrial and Science and Technology, Grid Technology Research Cente, JP Development and Characterization of a 2D microchipbased Protein separation system. J.J. Feng, V Olazabal, J.A. Olivares, S. Sundaram, S. Krishnamoorthy and S. Iyer Los Alamos National Laboratory, US Amplification of Protein Adsorption on Micro/Nanostructures for Microarray Applications E.P. Ivanova, Y.V. Alekseeva, D.K. Pham, L. Filipponi and D.V. Nicolau Swinburne University, AU Evaluation of Electric Impedance Spectra for Single BioCells with Microfluidic Devices using Combined FEMLAB/HSPICE Simulated Models V. Senez, T. Yamamoto, B. Poussard, T. Fukuba, J.M. Capron and T. Fujii LIMMS/CNRSIIS University of Tokyo, JP Chapter 3: Bio Molecular Motors Actin Adsorbed on HOPG and Mica Substrates: Characterization and Manipulation by Atomic Force Microscopy D.V. Nicolau, G.S. Watson, C. Cahill, J. Blach and S. Myhra Swinburne University, AU A Molecular Motor that Links the Biological and Silicon Worlds T. Robinson, A. Blundell, C.F. Dutta and K. Firman University of Portsmouth, UK Viral Protein Linear (VPL) NanoActuators A. Dubey, G. Sharma, C. Mavroidis, S.M. Tomassone, K.P. Nikitczuk and M.L. Yarmush Northeastern University, US Biomimetic Molecules as Building Blocks for Synthetic Muscles A Proposal A.H. Flood, J. Badjic, JY Han, C. Pentecost, B.H. Northrop, S.J. Cantrill, K.N. Houk and J.F. Stoddart UCLA and CNSI, US MEMS Biofluidic Device Concept Based on a Supramolecular Motor M.J. Knieser, R. Pidaparti, F. Kadioglu, R.D. Harris, M.R. Knieser and A. Hsu Indiana Univerisity Purdue University Indianapolis, US A Mechanistic Model of the Motility of Actin Filaments on Myosin D.V. Nicolau_Jr. and D.V. Nicolau Swinburne University, AU A Proposal Conceptualization of a Hybrid BioMotoReductor Actuator and the "Virtual Shaft" Hypothesis M.A. Venegas Nano Science and Technology Institute, MX Chapter 4: Ion Channels The Dielectric Boundary Force in Ion Channels: The Case of Gramicidin B. Nadler, U. Hollerbach and R.S. Eisenberg Yale University, US Brownian Dynamics Simulation of Transport Properties in Potassium Ion Channels S. Aboud, D. Marreiro, M. Saraniti and R.S. Eisenberg IIT/Rush University, US BioMOCA: A Transport Monte Carlo Approach to Ion Channel Simulation T.A. van der Straaten, G. Kathawala and U. Ravaioli Beckman Institute, University of Illinois, US Hybrid MDPNP Simulations of the AlphaHemolysin Open Ion Currents I. Cozmuta, J.T. O'Keeffe and V. Stolc Eloret Corp, NASA Ames Research Center, US Toward an Integrated Computational Environment for Multiscale Computational Design of Nanoscale Ion Channel Semiconductors S. Natarajan, S. Varma, Y. Tang, S. Parker, J. Mashl and E. Jakobsson NCSA, US Chapter 5: Bio Nano Computational Methods and Applications Numerical Modeling of Diffusion in Extracellular Space of Biological Cell Clusters and Tumors J. Berthier, F. Rivera and P. Caillat CEALETI, FR Mathematical Modeling for Immunocolloid Labeling C. Raymond and P. Milewksi New Jersey Institute of Technology, US Crystallization of Membrane Protein Nanoparticles A. Shiryayev, E.F. Holby and J.D. Gunton Lehigh University, US Monte Carlo Study of Models of Membrane Proteins T.P. Connor, D.L. Pagan, A. Shiryayev and J.D. Gunton Lehigh University, US Biomolecule Electrostatic Optimization with an Implicit Hessian J.P. Bardhan, J.H. Lee, M.D. Altman, S. Leyffer, S. Benson, B. Tidor and J.K. White Massachusetts Institute of Technology, US Self Assembly of Globular Protein Nanoparticles A. Shiryayev and J.D. Gunton Lehigh University, US A Monte Carlo Study of a Model of Globular Protein Nanoparticles D.L. Pagan, M.E. Gracheva and J.D. Gunton Lehigh University, US DNA and Estrogen Receptor Interaction Revealed by the Fragment Molecular Orbital Method Implementation of SCF Convergence T. Watanabe, Y. Inadomi, S. Tanaka and U. Nagashima National Institute of Advanced Industrial and Science and Technology, JP Development of an Advanced Simulation System for the Analysis of Particle Dynamics in LASER based Protein Ion Sources A. Hieke Ciphergen Biosystems, Inc., US Resolved Particle Simulations of Microsphere/Cellbased Bioanalytic Systems K. Pant, B.F. Romanowicz and S. Sundaram CFD Research Corporation, US Chapter 6: Bio Micro Sensors and Systems Modeling of the Dielectrophoretic Forces Acting upon Biological Cells: A Numerical Comparison between Finite Element/Boundary Element Maxwell Stress Tensor Methods and Dipole Point Approach A. Benselama, P. Pham, Ae. Canot CEA, FR An Approach for Fabrication of Polymerbased Bioanalytical Microfluidic Devices M. Wang, KY Weng, CC Huang, WP Liu and LY Yao Industrial Technology Research Institute, TW A Generic Sensor for Ultra Low Analyte Concentration Detection J. Hedley, C.J. McNeil, J.S. Burdess, A.J. Harris, M.G. Dobson, G. Suarez and H. Berney Newcastle University, UK Characterization of Micropumps for Biomedical Applications Y. Haik, J. Hendrix, M. Kilani, P. Galambus and CJ Chen Florida State University, US Modeling of Dielectrophoresis for Handling Bioparticles in Microdevices G.F. Yao Flow Science Inc., US QuadruptletsMicroneedle Array for Blood Extraction S. Khumpuang, G. Kawaguchi and S. Sugiyama Ritsumeikan University, JP A Disposable Glucose Biosensor Based on Diffusional Mediator Dispersed in Nanoparticulate Membrane on ScreenPrinted Carbon Electrode Z. Gao, F. Xie, M. Shariff, M. Arshad and J.Y. Ying Institute of Bioengineering and Nanotechnology, SG A Microfluidic System with Nonenzymatic Glucose Sensor S. Joo, S. Park, H. Lim, T.D. Chung and HC Kim Seoul National University, KR Glucometers to Detect for Heart Attack Y. Haik, A. Qablan, A. Zwolinski, CJ Chen Florida State University, US Optical Detection of Integrin AvB3 Using a Nanostructured Lipid Bilayer Membrane Biosensor O. Worsfold and T. Nishiya Fujirebio Inc., JP MicroPatterning of Ionic Reservoirs within a Double Bilayer Lipid Membrane to Fabricate a 2D Array of IonChannel Switch Based Electrochemical Biosensors J.M. Sansinena, C.K. Yee, A. Sapuri, B.I. Swanson, A. Redondo and A.N. Parikh Los Alamos National Laboratory, US Potentiometric Biosensors Based on Silicon and Porous Silicon I. Basu, R.V. Subramanian, A. Mathew, A. Chadha and E. Bhattacharya Indian Institute of Technology Madras, IN BioImpedance Sensing Device (BISD) for Detection of Human CD4+ Cells N.N. Mishra, S. Retterrer, T.J. Zieziulewicz, M. Isaacson, D. Szarowski, D.E. Mousseau, D.A. Lawrence and J.N. Turner New York City Department of Health, US Behavior of Living Human Neural Networks on Microelectrode Array Support R. Pizzi, F. Gelain, A. Fantasia, D. Rossetti and A. Vescovi University of Milan, IT Glucose Sensors Based on Glucose Oxidase Immobilized in PolypyrrolePolyacrylamide Microparticles E. LopezCabarcos, J. RubioRetama, D. Mecerreyes and B. LopezRuiz University Complutense, ES Chapter 7: Micro Fluidics and Nanoscale Transport Nanostructure and Phase Transitions in the Liquid Phase of Metallic and Nonmetallic Elements G.C. Vezzoli Institute for the Basic Sciences, US Application of Local Radial Basis Functionbased Differential Quadrature Method in Micro Flows D. Xu, H. Ding and C. Shu Agency for Science Technology and Research, SG Numerical Visualization and Quantification of Chaotic Mixing for Micromixers T.G. Kang and T.H. Kwon Pohang University of Science and Technology, KR A Low Cost Polymer Based PiezoActuated Micropump for Drug Delivery System H. Liu, A.A.O. Tay, S.Y.M. Wan and G.C. Lim Institute of Materials Research & Engineering, SG Galilean Invariant Viscosity Term for an Athermal Integer Lattice Boltzmann Automaton in three Dimensions M.C. Geier, A. Greiner and J.G. Korvink IMTEK, Albert Ludwigs University Freiburg im Breisgau, DE Liquid Disintegration: Investigation of Physics by Simulation J. Zeng and T. Korsmeyer Coventor, Inc., US Capillary Passive Valve in Microfluidic System H. Cho, HY Kim, J.Y. Kang and T.S. Kim Microsystem Research Center, Korea Institute of Science and Technology, KR Clogging Pressures of Bubbles in Microchannel Contractions: Theory and Experiments M.J. Jensen, X. Wang, D. Attinger and H. Bruus Mikroelektronik Centret, DTU, DK InPlane Micropump: Design Optimization J. Sin, W.H. Lee and H.E. Stephanou RPI, US Analysis of Blood Extraction from a Lancet Puncture R.J. Kuriger and B.F. Romanowicz CFD Research Corporation, US Polymeric Micropump with SU8 Check Valves Assembled by Lamination Technique T.Q. Truong and N.T. Nguyen Nanyang Technological University, SG Electrokinetic Instability Mechanism of Doublelayered Miscible Fluids with Different Electrolyte Concentrations in DC Electric Field J.W. Park, K.H. Kang and K.Y. Huh Pohang University of Science and Technology, KR Flow Simulation of a Microfluidic Analog of the FourRoll Mill F.R. Phelan_Jr. and S.D. Hudson NIST, US SOI Processing of a Ring Electrokinetic Chaotic Micromixer Y.T. Zhang, H. Chen, I. Mezic, C.D. Meinhart, L. Petzold and N.C. MacDonald university of california, santa barbara, US Spacific Flow Control Systems Using IR Laser Induced SolGel Transfer of Hydrogel J. Tanaka, Y. Shirasaki, M. Tatsuoka, T. Funatsu, S. Watabe, S. Shoji, T. Edura, J. Mizuno and Y. Wada Waseda University, JP Optimization of Mixing in an Active Micromixing Device G. Mathew, I. Mezic, R. Serban and L. Petzold University of California, Santa Barbara, US Droplet Movement Induced by Nano Assembled Molecules And Micro Textures FG Tseng and S.C. Chien National Tsing Hua University, ESS Dept., TW Analysis of ACDriven Electroosmotic Flow in a Microchannel Packed with Microspheres Y.J. Kang, C. Yang and X.Y. Huang Nanyang Technological University, SG An Effective Passive Micromixer Employing Herringbone Structure CF Kung, CF Chen, CC Chu and FG Tseng IAM, National Taiwan University, TW Novel 2D Interfaces for NanoelectrosprayMass Spectrometry S. Arscott, S. Le Gac, C. Druon, P. Tabourier and C. Rolando USTL, FR DEP Particle Dynamics and the Steady Drag Assumption S.T. Wereley, I. Whitacre, R. Bashir and H.B. Li Purdue University, US Chapter 8: MEMS Design and Application A New Method to Design Pressure Sensor Diaphragm X. Wang, B. Li, S. Lee, Y. Sun, H.T. Roman, K. Chin and K.R. Farmer New Jersey Institute of Technology, US Lattice Boltzmann Simulations Comparing Conventional and a Heat Conduction Based FlowThrough PCR MicroDevices T. Mautner SPAWAR Systems Center San Diego, US Geometrical Effects in Mechanical Characterizing of Microneedle for Biomedical Applications P. Aggarwal and C. Johnston University of Calgary, CA Design and Manufacturing of a Miniaturized 2.45GHz Bulk Acoustic Filter by High Aspect Ratio Etching Process CH Lin, HR Chen, CH Du and W. Fang National TsingHua University, TW A MEMS Tunable Inductor I. ZineElAbidine, M. Okoniewski and J.G. McRory University of Calgary and TRLabs, CA Design & Simulation of a Mechanical Amplifier for Inertial Sensing Applications M.N. Kham, R. Houlihan and M. Kraft Southampton University, UK Micromachined Thermal Multimorph Actuators Fabricated by Bulketched MUMPs Process A. Tuantranont and V.M. Bright National Electronics and Computer Technology Center (NECTEC), TH Micromachined Piezoresistive Tactile Sensor Array Fabricated by Bulketched MUMPs Process A. Tuantranont, T. Lomas and V.M. Bright National Electronics and Computer Technology Center (NECTEC), TH Modelling and Fabrication of Microspring Thermal Actuator J.K. Luo, A.J. Flewitt, M. Spearing, N.A. Fleck and W.I. Milne University of Cambridge, UK The Application of Parametric Excitation to a MicroRing Gyroscope B.J. Gallacher, J.S. Burdess, A.J. Harris and J. Hedley Insat University of Newcastle, UK A Nanoscale Composite Material for Enhanced Damage Tolerance in MEMS Applications A. Paranjpye, N.C. MacDonald and G.E. Beltz University of California, Santa Barbara, US Novel Monolithic Micro Droplet Generator C.K. Chung, C.J. Lin, C.C. Chen, S.W. Chuang, Y.J. Fang and Y.Z. Hong National Cheng Kung University, TW A Novel Fabrication Technique of Cylindrical Ion Traps using Low Temperature Cofired Ceramic Tapes A. Chaudhary, F.H.W. van Amerom, S. Bhansali and R.T. Short University of South Florida, US Micromachined IIIV Multimorph Actuator Model and Design using Simulated Annealing (SA)Based Global Optimization A. Ongkodjojo, F.E.H. Tay and R. Akkipeddi Institute of Materials Research & Engineering, SG Optimized Distributive uMixing by Chaotic Multilamination F. Schonfeld, K.S. Drese, S. Hardt, V. Hessel and C. Hofmann Institut fur Mikrotechnik Mainz -(IMM), DE Analysis of Micromachined PZT Membranes for MEMS Power J.H. Cho, M.J. Anderson, R.F. Richards, D.F. Bahr, and C.D. Richards Washington State University, US Integrated High Frequency RF Inductors with Nano/micro Patterned Ferromagnetic Cores Y. Zhuang, M. Vroubel, B. Rejaei and J.N. Burghartz Delft University of Technology, NL TwoRegime Hollow PDMS Abbe Prism for uTAS Applications A. Llobera, R. Wilke and S. Buttgenbach Institut fur Mikrotechnik, DE Device Characterization at the Wafer Level via Optical Actuation and Detection J. Hedley, J.S. Burdess, A.J. Harris and B.J. Gallacher Newcastle University, UK A MOEMS Electrothermal Grating E.P. Furlani Eastman Kodak Research Labs, US Practical Techniques for Measuring MEMS Properties J.V. Clark, D. Garmire, M. Last, J. Demmel and S. Govindjee Berkeley Sensor and Actuator Center, US Pumping Capacity and Reliability Study on SiliconBased Cryogenic Micro Pump Y. Zhao, B. Li, D. Ludlow and X. Zhang Boston University, US Chapter 9: Smart MEMS and Sensor Systems System Issues in Arrays of Autonomous Intelligent Sensors R.M. Newman and E.I. Gaura Conventry University, UK Simulation of Micromachined Inertial Sensors with HigherOrder Single Loop SigmaDelta Modulators Y. Dong and M. Kraft University of Southampton, UK Design and Development of an Integrated MEMS Sensor for Real Time Control of Plasma Etching B.G. Morris and G.S May Georgia Institute of Technology, US GEMS: A Revolutionary System for Environmental Monitoring J. Manobianco, R.J. Evans, K.S.J. Pister and D.M. Manobianco ENSCO, Inc., US Resonant Frequency Shift of Torsional Acutators due to Electrostatic Force Z. Xiao, Y. Sun, B. Li, S. Lee, K.S. Sidhu, K.K. Chin and K.R. Farmer New Jersey Institute of Technology, US Electrostatic Tuning of a MicroRing Gyroscope B.J. Gallacher, J. Hedley, J.S. Burdess, A.J. Harris, A. Rickard and D. King Insat University of Newcastle, UK Macromodel of Intelligent Sensor Structure with Accelometer M. Husak, J. Jakovenko, P. Kulha, J. Novak and V. Janicek Czech Technical University in Prague, CZ Modeling and Practial Verification of the Ionophore Based Chemically Modified Field Effect Transistor M. Daniel, M. Szermer, M. Janicki and A. Napieralski DMCS, Technical University of Lodz, PL Smart, Intelligent and Cogent Microsensors Intelligence for Sensors and Sensors for Intelligence E. Gaura and R.M. Newman Coventry University, UK Chapter 10: Micro and Nano Structuring and Assembly Soft and Probe Lithography without Ink Transfer J. Huskens, X. Li, M. Peter and D.N. Reinhoudt University of Twente, MESA+ Research Institute, NL Ferrofluid Masking for Lithographic Applications B. Yellen and G. Friedman Drexel University, US Micro Actuator Array based on Ionic Polymer with Patterned SelfAssembled Au Electrode M. Le Guilly, C. Xu, M. Taya and Y. Kuga University of Washington, US Batch Fabrication of Microsensor Arrays by TiO2 Nanoparticle Beam Deposition P. Milani, E. Barborini, P. Piseri, S. Iannotta and P. Siciliano Universita' di Milano, IT Direct Scanning Laser Writing of 3D Multilayer Microstructures H. Yu, B. Li and X. Zhang Boston University, US BottomUp meets TopDown A Novel Approach towards 3D Optical Devices R. Houbertz, S. Cochet, G. Domann, M. Popall, J. Serbin, A. Ovsianikov and B.N. Chichkov Fraunhofer ISC, DE A Novel Method for Determining Optimum Etch Times for the One Step Dry Release Proces P.T. Docker, P.K. Kinnell and M.C. Ward The University of Birmingham, UK Chapter 11: Wafer and MEMS Processing Planarize the Sidewall Ripples of Silicon Deep Reactive Ion Etching KY Weng, MY Wang and PH Tsai Industrial Technology Research Institute, TW Process Factors in the Reduction of Output Conductance in Submicron CMOS N.C. May, H.S. Tan and A.V. Kordesch SILTERRA (M) SDN BHD, MY Inverse RIE Lag of Silicon Deep Etching C.K. Chung and H.N. Chiang National Cheng Kung University, TW Microscope Slide Electrode Chamber for Nanosecond, MegavoltPerMeter Biological Investigations Y. Sun, P.T. Vernier, M. Behrend, L. Marcu and M.A. Gundersen University of Southern California, US Numerical Analysis of Nanoimprinting Process Based on Continuum Hypothesis H.C. Kim, Y.S. Woo, W.I. Lee, S.I. Oh and B.S. Kim School of Mechanical and Aerospace Engineering, Seoul National University., KR