Contributors | p. vii |
Preface | p. ix |
Regulation of Alkaloid Biosynthesis in Plants | |
Introduction | p. 1 |
Alkaloid Biosynthetic Pathways | p. 2 |
Regulation of Alkaloid Biosynthesis | p. 16 |
Applications of Genomics to the Study of Alkaloid Biosynthesis | p. 28 |
Metabolic Engineering of Alkaloid Pathways | p. 29 |
Future Prospects | p. 34 |
Acknowledgments | p. 35 |
References | p. 35 |
Ergot Alkaloids - Biology and Molecular Biology | |
Introduction | p. 45 |
Through the Ages: A History of Ergot Alkaloid Use, Abuse, and Poisoning | p. 48 |
Ergot Alkaloid Producers | p. 50 |
Biosynthetic Pathways and Genes | p. 53 |
Routine Analytical Methods for Ergot Alkaloids | p. 75 |
Ergot Alkaloid Activities and Roles | p. 76 |
Summary and Conclusions | p. 80 |
Acknowledgments | p. 82 |
References | p. 82 |
Chemical and Biological Aspects of Narcissus Alkaloids | |
Introduction | p. 87 |
Narcissus Alkaloids and their Occurrence | p. 91 |
Biosynthetic Pathways | p. 99 |
Synthetic Studies | p. 114 |
Spectroscopy and Alkaloid Data | p. 127 |
Biological and Pharmacological Activities | p. 153 |
References | p. 163 |
Bisindole Alkaloids | |
Introduction | p. 182 |
Indole-Indole and Tryptamine-Tryptamine Type, and Related Alkaloids | p. 182 |
Tryptamine-Tryptamine Type with an Additional Monoterpene Unit and Related Alkaloids | p. 216 |
Corynanthe-Tryptamine Type | p. 217 |
Corynanthe-Corynanthe Type | p. 223 |
Corynanthe-Strychnos Type | p. 224 |
Vobasine-Tryptamine Type | p. 228 |
Vobasine-Vobasine Type | p. 228 |
Vobasine-Akuammiline Type | p. 230 |
Vobasine-Vincorine Type | p. 231 |
Bisindole Alkaloids from Alstonia | p. 231 |
Akuammiline-Ajmaline Type | p. 240 |
Ajmaline-Vincorine Type | p. 242 |
Akuammiline-Vincorine Type | p. 243 |
Akuammiline-Pleiocarpamine Type | p. 245 |
Vincorine-Vincorine Type | p. 245 |
Strychnos-Vobasine Type | p. 247 |
Strychnos-Strychnos Type | p. 248 |
Secodine-Secodine Type | p. 255 |
Apparicine-Vobasine Type | p. 255 |
Ellipticine-Ellipticine Type | p. 257 |
Iboga-Vobasine Type | p. 258 |
Iboga-Iboga Type | p. 269 |
Aspidosperma-Vobasine Type | p. 270 |
Aspidosperma-Vincorine Type | p. 270 |
Aspidosperma-Macroline Type | p. 271 |
Aspidosperma-Iboga Type | p. 273 |
Aspidosperma-Aspidosperma Type | p. 274 |
Aspidosperma-Pseudoaspidosperma Type | p. 286 |
Aspidosperma-Eburnea Type | p. 289 |
Aspidosperma-Canthinone Type | p. 294 |
Eburnea-Eburnea Type | p. 297 |
Miscellaneous Bisindole Alkaloids | p. 298 |
Aspidosperma-Cleavamine Type | p. 300 |
References | p. 322 |
Cumulative Index of Titles | p. 339 |
Index | p. 347 |
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