The Aspergilli : Genomics, Medical Aspects, Biotechnology, and Research Methods - Gustavo H. Goldman

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The Aspergilli

Genomics, Medical Aspects, Biotechnology, and Research Methods

By: Gustavo H. Goldman (Editor), Stephen A. Osmani (Editor)

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Hardcover | 7 December 2007 | Edition Number 1

At a Glance

Hardcover
576 Pages

Dimensions(cm)
26.1 x 18.5 x 3.5

Hardcover

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With high-quality genome sequences for the important and ubiquitous Aspergilli now available, increased opportunities arise for the further understanding of its gene function, interaction, expression, and evolution. The Aspergilli: Genomics, Medical Aspects, Biotechnology, and Research Methods provides a comprehensive analysis of the research that reveals the main biological attributes of these species. The co-editors are a particularly proficient and prolific pair with long track records of scientific productivity.

The book sets the stage with a discussion of basic biology, examining the data on the structure of genomes and comparing the genetic map and annotation methodology. It includes a comparison of metabolic abilities among different Aspergillus spp. and other species, then covers areas such as comparative biology, pathogenic properties, and metabolic capabilities of the Aspergilli. The book reviews established techniques and new methodologies for the post-genomic era in Aspergillus spp. It comes with a CD containing color illustrations to supplement the text.

Filling the need for centralized information on a genus that has important economic impacts on agriculture, human health, industry, and pharmacology, the book presents a wide range of data, collected and arranged into one convenient resource. Written by a team of international experts, this is the first in-depth and exhaustive analysis of the genomics of the Aspergilli.

Industry Reviews

"The individual chapters are well-written, well-organized (with many very good figures and summary tables) and include recent data. I recommend this book, and it should be mandatory for those new to this field...this book would also be an excellecnt starting point for getting an overview of the current state of the field."

-Jan Lehmbeck, Society for General Microbiology, Feb. 2009

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Preface	p. xi
Editors	p. xiii
Contributors	p. xv
Genomics of the Aspergilli
An Overview of the Genus Aspergillus	p. 3
A First Glance into the Genome Sequence of Aspergillus flavus	p. 15
A Comparative View of the Genome of Aspergillus fumigatus	p. 25
Aspergillus nidulans Genome and a Comparative Analysis of Genome Evolution in Aspergillus	p. 43
Aspergillus nidulans Linkage Map and Genome Sequence: Closing Gaps and Adding Telomeres	p. 57
Genome Sequence of Aspergillus oryzae	p. 75
Basic Biology of the Aspergilli
Signal Transduction in Aspergilli	p. 87
Gene Regulation	p. 103
Mitogen-Activated Protein Kinase Pathways in Aspergilli	p. 121
Gluconeogenic Carbon Metabolism	p. 129
Amino Acid Supply of Aspergillus	p. 143
Endocytosis	p. 177
RNA Silencing in the Aspergilli	p. 197
Hyphal Morphogenesis in Aspergillus nidulans	p. 211
Cytoskeleton, Polarized Growth, and the Cell Cycle in Aspergillus nidulans	p. 223
Nuclear Pore Complex and Transport in Aspergillus nidulans	p. 261
Sexual Development in Aspergillus nidulans	p. 279
Aspergillus Transporters	p. 301
Chromatin in the Genus Aspergillus	p. 321
Transposable Elements and Repeat-Induced Point Mutation in Aspergillus nidulans, Aspergillus fumigatus, and Aspergillus oryzae	p. 343
Medically Important Aspects of the Genus
Clinical Aspects of the Genus Aspergillus	p. 359
Pathogenicity Determinants and Allergens	p. 377
Mammalian Models of Aspergillosis	p. 401
Emerging Role of Mini-Host Models in the Study of Aspergillosis	p. 413
Biotechnological Aspects of the Genus
Food Products Fermented by Aspergillus oryzae	p. 429
Aspergillus as a Cell Factory for Protein Production: Controlling Protease Activity in Fungal Production	p. 441
Mycotoxin Production and Prevention of Aflatoxin Contamination in Food and Feed	p. 457
Methods: Techniques and Resources
Microarrays in Aspergillus Species	p. 475
Chemostats and Microarrays	p. 483
Advances in Gene Manipulations Using Aspergillus nidulans	p. 493
Fluorescent Labels for Intracellular Structures and Organelles	p. 513
Aspergillus at the Fungal Genetics Stock Center	p. 527
Index	p. 537
Table of Contents provided by Ingram. All Rights Reserved.

The Aspergilli

Genomics, Medical Aspects, Biotechnology, and Research Methods

At a Glance

Hardcover

Industry Reviews

Shipping

How to return your order

Defective items

You Can Find This Book In

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