The Genetics and Development of Scoliosis

By: Kenro Kusumi (Editor), Sally L. Dunwoodie (Editor)

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Paperback | 15 January 2019 | Edition Number 2

At a Glance

Paperback
212 Pages

Edition Type
Revised

Dimensions(cm)
23.39 x 15.6 x 1.14

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$187.31

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Our understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis is to provide researchers, clinicians, and students with the most current views in this field.

This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.

Industry Reviews

"The book is aimed at researchers, clinicians, and students involved in the treatment of patients with idiopathic and congenital scoliosis. Orthopedic surgeons, rehabilitation specialists, clinical geneticists, and primary care providers in particular may find information about abnormal spinal curvatures of interest. ... Not many books are exclusively dedicated to specific genetic disorders such as this one. ... This is a well-done review that will be a useful consultation resource for clinicians." (Luis F Escobar, Doody's Book Reviews, January 31, 2020)

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