| Preface | |
| List of Contributors | |
| Menopause as a Medical and Social Issue | |
| The Problem of Menopause in Europe | p. 1 |
| Menopause: Problems and Interventions in the United States | p. 9 |
| Hormone Replacement Therapy and Oral Contraceptives: Limitations of Epidemiological Studies | p. 15 |
| Ovarian Senescence | |
| Genetic Factors in Follicular Aging | p. 25 |
| Premature Menopause | p. 29 |
| When Should Hormonal Replacement Therapy Be Introduced? Associated Problems | p. 39 |
| Connective Tissue and Bone | |
| Connective Tissue Changes | p. 45 |
| The Effect of Low Dose Estrogen on Bone Mass in the Late Postmenopausal Years | p. 55 |
| Perimenopausal Changes in Body Weight, Body Fat Distribution, and Hormonal Replacement Therapy | p. 61 |
| Osteoporosis | |
| The Effects of Estrogen Receptor Gene Disruption on Bone | p. 69 |
| Osteoporosis: Different Treatment Options | p. 75 |
| Inherited Risk of Osteoporosis: A Piece in the Puzzle of Menopause Genetics | p. 79 |
| Estrogen Replacement Therapy And Osteoporosis: Practical Implications Of New Research Findings | p. 87 |
| Cardiovascular Risk | |
| HRT, Plasma Risk Factors, and Cardiovascular Disease | p. 91 |
| Menopause, HRT, and Hemostasis | p. 99 |
| Angina in Women | p. 105 |
| Effect of Estrogen on Anatomical and Functional Sequelae of Coronary Artery Disease | p. 111 |
| Cardiovascular Disease: Reduced Mortality with Long-Term HRT Treatment | p. 119 |
| HRT and The Secondary Prevention Of Coronary Heart Disease | p. 125 |
| Vascular Biology | |
| Effects of Hormone Replacement Therapy on Lipids and Lipoproteins in Dyslipidemic Postmenopausal Women: A Comparison Between Transdermal and Oral Estrogen | p. 129 |
| Which Effects Does Early HRT Have on Perimenopausal Changes in the Lipoprotein Profile, Glucose Metabolism, and Blood Coagulation-Fibrinolysis System? | p. 135 |
| Blood Flows in Cerebral Arteries after Suspension of Postmenopausal Hormone Replacement Therapy. A Randomized Crossover Study | p. 141 |
| Influence of Melatonin on the Internal Carotid Artery Pulsatility Index of Young and Aged Women | p. 145 |
| Cognitive Processes and Dementia in Elderly Women | |
| Epidemiology of Alzheimer's Disease and Other Types of Dementias | p. 149 |
| Estrogen Replacement Therapy and Cognitive Functions in Elderly Women | p. 163 |
| Hormonal Replacement Therapy, Cognitive Disturbances, and Alzheimer's Disease | p. 169 |
| Central Nervous System | |
| Hormone Replacement Therapy in the Prevention and Treatment of Climacteric Depression | p. 177 |
| Estrogen Across the Lifespan and Alzheimer's Disease | p. 185 |
| Estrogen Effect on Brain Biology and Cognition | p. 191 |
| Dysphoria and Mood Disorders in Menopause | p. 199 |
| A Model System for the Study of Estrogen Receptor Activity in Cells of Neural Origin | p. 209 |
| Neoplasia | |
| The Risk of Breast Cancer in Relation to Hormone Replacement Therapy | p. 217 |
| Potential Benefits of Estrogen and Progestogen on Malignancy | p. 223 |
| Hormone Replacement Therapy After Breast Cancer | p. 233 |
| HRT and the Endometrium | |
| Endometrial Histology: Findings from the Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial | p. 241 |
| Effects of Quarterly Hormone Replacement Therapy on Climacteric Symptoms, Endometrial Safety, and Lipoproteins | p. 247 |
| HRT: Addressing the Needs of Women and Physicians | |
| Individualization of Hormone Replacement Therapy | p. 253 |
| Clinical Experiences with a Combination of Estradiol Valerate and Cyproterone Acetate for Hormone Replacement | p. 257 |
| HRT: From Motivation to Compliance | p. 263 |
| The Overall Benefit and Safety Profile of CEE+MPA in a Continuous Sequential or Combined Regimen | |
| The Pharmacologic Profile of Conjugated Equine Estrogens | p. 275 |
| Hormone Replacement Therapy with Conjugated Equine Estrogens and Medroxyprogesterone Acetate | p. 283 |
| Bleeding Patterns and Compliance with CEE plus MPA Continuous Sequential or Combined Regimens in Postmenopausal Women | p. 289 |
| CEE-MPA: A Relevant Reduction in Cardiovascular Disease Risk | p. 295 |
| Hormone Replacement Therapy and Breast and Gynecologic Cancers | p. 303 |
| New Drugs and Alternative Treatment | |
| Raloxifene HCl: A Tissue Selective Estrogen Receptor Modifier (SERM) for Replacement Therapy in Postmenopausal Women | p. 315 |
| Dietary Phyto-Estrogens and the Menopause | p. 321 |
| Primary and Secondary Prevention of Cardiovascular Diseases in Menopausal Women: Alternative Treatment to Hormonal Replacement Therapy | p. 327 |
| Index | p. 339 |
| Table of Contents provided by Blackwell. All Rights Reserved. |
