eTEXT

Neurodegenerative Diseases

Translational Models, Mechanisms, and Therapeutics

By: Sachchida Nand Rai (Editor), Sandeep Singh (Editor), Santosh Kumar Singh (Editor)

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eText | 2 December 2024 | Edition Number 1

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This reference book provides a comprehensive overview of models and therapeutic approaches against neurodegenerative diseases, including Parkinson's disease, Alzheimer's disease, Huntington's disease, and amyotrophic lateral sclerosis. It explores models based on the chemical, induced, cellular, genetic, transgenic, and 3D organoid approaches in neurodegenerative diseases. The book also reviews advantages and limitations of these models in designing the treatment strategies. Additionally, the book covers the emerging field of bioinformatics and its application in modeling various neurodegenerative diseases. Towards the end, the book highlights the role of holistic management, precision medicine, OMICS, and gene therapy against neurodegenerative disorders. It examines the implications and significance of stem cells therapy in translational models of neurodegenerative diseases. This book is an invaluable resource for researchers, neuroscientists, and neurosurgeons for getting in-depth information on the neurodegenerative models and therapeutic approaches.

Key Features:

Provides a comprehensive overview of neurodegenerative diseases and their models
Examines the limitations associated with modeling neurodegenerative diseases
Presents novel treatment strategies for Alzheimer's disease using cellular models
Reviews importance of 3D organoid models for therapeutic approaches in Parkinson's disease
Covers modeling techniques in understanding prion diseases
Explores the role of genetic models in understanding Huntington's disease