The Histone Code and Beyond : New Approaches to Cancer Therapy - Shelley L. Berger

eTEXT

The Histone Code and Beyond

New Approaches to Cancer Therapy

By: Shelley L. Berger, ?O. Nakanishi, ?Bernhard Haendler

eText | 19 January 2007 | Edition Number 1

At a Glance

eText


$159.01

or 4 interest-free payments of $39.75 with

 or 

Instant online reading in your Booktopia eTextbook Library *

Read online on
Desktop
Tablet
Mobile

Not downloadable to your eReader or an app

Why choose an eTextbook?

Instant Access *

Purchase and read your book immediately

Read Aloud

Listen and follow along as Bookshelf reads to you

Study Tools

Built-in study tools like highlights and more

* eTextbooks are not downloadable to your eReader or an app and can be accessed via web browsers only. You must be connected to the internet and have no technical issues with your device or browser that could prevent the eTextbook from operating.
Methylation of DNA at cytosine residues as well as post-translational modifications of histones, including phosphorylation, acetylation, methylation and ubiquitylation, contribute to the epigenetic information carried by chromatin. These changes play an important role in the regulation of gene expression by modulating the access of regulatory factors to the DNA. The use of a combination of biochemical, genetic and structural approaches has allowed demonstration of the role of chromatin structure in transcriptional control. The structure of nucleosomes has been elucidated and enzymes involved in DNA or histone modifications have been extensively characterized. Since deregulation of epigenetic marks has been reported in many cancers, a better understanding of the underlying molecular mechanisms bears the promise that new drug targets may soon be found. The newest developments in this quickly developing field are presented in this book.
Read online on
Desktop
Tablet
Mobile

More in Biochemistry

Tissue Proteomics : Methods and Protocols - Taufika Islam Williams

eBOOK

RRP $379.00

$341.99

10%
OFF
SNAREs : Methods and Protocols - Rutilio Fratti

eBOOK

RRP $329.00

$296.99

10%
OFF
Metabolic Profiling : Methods and Protocols - Olga Deda

eBOOK

RRP $359.00

$323.99

10%
OFF
Biophysical Chemistry - Dagmar Klostermeier

eTEXT